Category: 42538-31-8

Electric Literature of 42538-31-8, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 42538-31-8, Name is (S)-3-Aminopiperidin-2-one hydrochloride, molecular formula is C5H11ClN2O. In a Article£¬once mentioned of 42538-31-8

NEW CHIRAL AMINOPHOSPHINES PREPARED FROM L-ORNITHINE AND CATALYTIC ASYMMETRIC HYDROGENATION USING THEIR RHODIUM(I) COMPLEXES

From readily preparable chiral diamines were obtained new aminophosphines, (3S)--3-aminopiperidine, and (3S)--3-(methylamino)piperidine.Asymmetric hydrogenation of alpha-acylaminoacrylic acids, employing Rh(I) complexes with these aminophosphines as catalyst, gave optically active N-acyl-alpha-amino acids.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Electric Literature of 42538-31-8, you can also check out more blogs about42538-31-8

Reference£º
Piperidine – Wikipedia,
Piperidine | C5H8311N – PubChem

 

42538-31-8,42538-31-8, (S)-3-Aminopiperidin-2-one hydrochloride is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

ExamEleJj_(5)-3-(l’-Methylcyclohexanecarbonyl)amino-tetrahydropyridin-2-one; (S)-3-Amino-tetrah.ydropyridin-2-one hydrochloride (2 mmol) and Na2CO3 (6 mmol) in water (25 ml) were added to a solution of 1-methylcyclohexanecarbonyl chloride (2 mmol) in dichloromethane (25 ml) at ambient temperature and the reaction was stirred for 18 hours. The organic layer was then separated and the aqueous phase was extracted with additional dichloromethane. The combined organic layers were dried over Na2SO4 and reduced in vacuo. The residue was purified by silica column chromatography (EtOAc: hexanes 1:3 to MeOH : EtOAc 1:19) to give as an amorphous solid (199 mg, 42%); v^/cm”1 3335, 3269 (NH)5 1650, 1621 (CO), 1529 (NH); deltaH (500 MHz, CDCl3) 6.65 (IH5 br d, J5, NH), 6.59 (IH5 br S5 NH), 4.18 (IH5 dt, J 11.5, 5.5, CHNH), 3.30 (2H, td, J6.5, 2.5, CH2NH), 2.52 (IH, ddt, J 13, 5.5, 4.5, lactam CH2), 1.92-1.83 (4H5 m, 2 x lactam CH and 2 x cyclohexane CH2), 1.55-1.23 (9H, m, lactam CH and 8 x cyclohexane CH2) and 1.11 (3H, s, CH3); deltac (125 MHz, CDCl3) 178.0, 172.3 (CO)5 50.4 (NHCHCO), 42.6 (CH3C quat), 41.5, 35.6, 35.5, 27.0 (CH2), 26.3 (CH3), 25.7, 22.8 (chi2), 20.9 (CH2); m/z (MNa+ C13H22N2O2Na requires 261.1579) 261.1570.

42538-31-8 (S)-3-Aminopiperidin-2-one hydrochloride 45789910, apiperidines compound, is more and more widely used in various fields.

Reference£º
Patent; CAMBRIDGE UNIVERSITY TECHNICAL SERVICES LIMITED; WO2006/134385; (2006); A2;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem