Category: 309962-63-8

Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent£¬ Safety of (S)-tert-Butyl methyl(piperidin-3-yl)carbamate, Which mentioned a new discovery about 309962-63-8

HETEROCYCLIC TYROSINE KINASE INHIBITORS

The present invention provides compounds useful as inhibitors of Tec family kinases, compositions thereof, and methods of using the same.

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 309962-63-8, help many people in the next few years.Safety of (S)-tert-Butyl methyl(piperidin-3-yl)carbamate

Reference£º
Piperidine – Wikipedia,
Piperidine | C5H16715N – PubChem

 

309962-63-8, (S)-tert-Butyl methyl(piperidin-3-yl)carbamate is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

A solution of 4-(6-fluoropyridin-3-yl)-6-(l-methyl-lH-pyrazol-4-yl)pyrazolo[l,5 a]pyrazine-3-carbonitrile (Intermediate P7; 0.100 g, 0.313 mmol) in DMSO (6.26 mL) was treated with (S)-tert-butyl methyl(piperidin-3-yl)carbamate (0.268 g, 1.25 mmol) and K2CCb(s) (0.173 g, 1.25 mmol) and stirred overnight at 110 C. After cooling to ambient temperature, the reaction mixture was diluted with water (10 mL) and extracted with DCM (4 x 10 mL) in a PS Frit. The combined organic extracts were concentrated in vacuo, and purified by C18 reverse phase chromatography (using 0-60% ACN/water as the gradient eluent) to afford the title compound (106 mg, 66% yield). MS (apci) m/z = 514.2 (M+H).

309962-63-8, 309962-63-8 (S)-tert-Butyl methyl(piperidin-3-yl)carbamate 28875358, apiperidines compound, is more and more widely used in various fields.

Reference£º
Patent; ANDREWS, Steven W.; BLAKE, James F.; HAAS, Julia; JIANG, Yutong; KOLAKOWSKI, Gabrielle R.; MORENO, David A.; REN, Li; WALLS, Shane M.; (421 pag.)WO2018/136661; (2018); A1;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem