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Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 29976-53-2, molcular formula is C8H13NO3, introducing its new discovery. Recommanded Product: N-Carbethoxy-4-piperidone

Sodium triacetoxyborohydride is presented as a general reducing agent for the reductive amination of aldehydes and ketones. Procedures for using this mild and selective reagent have been developed for a wide variety of substrates. The scope of the reaction includes aliphatic acyclic and cyclic ketones, aliphatic and aromatic aldehydes, and primary and secondary amines including a variety of weakly basic and nonbasic amines. Limitations include reactions with aromatic and unsaturated ketones and some sterically hindered ketones and amines. 1,2-Dichloroethane (DCE) is the preferred reaction solvent, but reactions can also be carried out in tetrahydrofuran (THF) and occasionally in acetonitrile. Acetic acid may be used as catalyst with ketone reactions, but it is generally not needed with aldehydes. The procedure is carried out effectively in the presence of acid sensitive functional groups such as acetals and ketals; it can also be carried out in the presence of reducible functional groups such as C-C multiple bonds and cyano and nitro groups. Reactions are generally faster in DCE than in THF, and in both solvents, reactions are faster in the presence of AcOH. In comparison with other reductive amination procedures such as NaBH3CN/MeOH, borane-pyridine, and catalytic hydrogenation, NaBH(OAc)3 gave consistently higher yields and fewer side products. In the reductive amination of some aldehydes with primary amines where dialkylation is a problem we adopted a stepwise procedure involving imine formation in MeOH followed by reduction with NaBH4.

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The present invention provides a process for producing cyclic thioether compounds and their synthetic intermediates.[Means for Solution]A compound represented by general formula (5): [wherein G1: alkylene, R1: a thiol protecting group, R2: hydrogen or an amino protecting group, and Ar: aryl group and so forth].

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Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 29976-53-2, molcular formula is C8H13NO3, introducing its new discovery. Computed Properties of C8H13NO3

The compounds of the invention are represented by the following general structure (I) or a pharmaceutically acceptable salt thereof, and compositions containing them, wherein the variables are defined herein, and their use to reduce or inhibit PTH secretion, including methods for reducing or inhibiting PTH secretion and methods for treatment or prophylaxis of diseases associated with bone disorders, such as osteoporosis, or associated with excessive secretion of PTH, such as hyperparathyroidism. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

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The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 29976-53-2 is helpful to your research. Reference of 29976-53-2

Reference of 29976-53-2, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.29976-53-2, Name is N-Carbethoxy-4-piperidone, molecular formula is C8H13NO3. In a Article,once mentioned of 29976-53-2

An efficient method is proposed for the preparation of substituted thieno<2,3-b:4,5-b'>dipyridines (2a-h, 3a-g, and 5a-e), based on the Friedlaender synthesis of 3-amino-5-cyano-7-ethoxy-2-formyl-4-phenylthieno<2,3-b>pyridine (1) with acyclic, cyclic, heterocyclic and alpha,beta-unsaturated ketones.In addition, the reaction of 1 with guanidine sulfate yielded the fused triheterocyclic pyrido<3',2':4,5>-thieno<3,2-d>pyrimidine system (6).

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A diverse set of N-methyl secondary amines are obtained in high yields by an expedient reductive alkylation of commercially available methanolic methylamine.

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A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, SDS of cas: 29976-53-2, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 29976-53-2, Name is N-Carbethoxy-4-piperidone, molecular formula is C8H13NO3. In a Patent, authors is ,once mentioned of 29976-53-2

2-Substituted-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido 4,3-b!indoles of the formula (I): STR1 and the pharmaceutically-acceptable salts thereof, wherein the hydrogen atoms in the 4a position and 9b positions are in a trans relationship to each other and the 5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido 4,3-b!indole moiety is dextrorotatory; X 1 and Y. sub.1 are the same or different and are each hydrogen or fluoro; Z 1 is hydrogen, fluoro or methoxy; M is a member selected from the group consisting of STR2 a mixture thereof and C=O and n is 3 or 4; their use as tranquilizing agents, pharmaceutical compositions containing them and a process for their production.

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This invention provides compounds that are antagonists of melanin concentrating hormone receptor-1 (MCH-R1). The compounds are represented by formula (I): where m is zero or one, n is zero to two, Y is oxygen or -N (R9)-, R1, R2, R3, R4, R5, R9, and Ring A are defined in the specification. Coumarin and quinolone compounds where R1 and R2 together form a fused benzo ring are preferred. The invention also provides compounds of formula (VI) where the coumarin moiety is replaced by a quinazolinone ring. The compounds are useful for treating MCH-R1-related disorders, particularly overweight conditions including obesity.

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The present invention relates to modulators of muscarinic receptors. The present invention also provides compositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.

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A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, Safety of N-Carbethoxy-4-piperidone, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 29976-53-2, Name is N-Carbethoxy-4-piperidone, molecular formula is C8H13NO3. In a Patent, authors is ,once mentioned of 29976-53-2

The invention relates to compounds of formula I, wherein Ra is -C(O)ORI , in which R1 is 1-7C-alkyl, 3-7C-cycloalkyl, or 1-7C-alkyl substituted by one to four substituents independently selected from R2, Rb is -T-Q, in which T is 1-6C-alkylene or 3-7C-cycloalkylene, and either Q is optionally substituted by Rba and/or Rbb and/or Rbc, and is phenyl or naphthyl, or Q is optionally substituted by Rca and/or Rcb, and is Har, or Q is optionally substituted by Rda and/or Rdb, and is Het, or Q is optionally substituted by Rea and/or Reb, and is 3-7C-cycloalkyl, which are useful for the therapy of hyperproliferative diseases, in particular human cancer.

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Cobalt pyridine?diimine (PDI) complexes catalyze the reductive spirocyclopropanation of terminal 1,3-dienes. gem-Dichlorocycloalkanes serve as carbene precursors and Zn is used as a terminal electron source. The reaction is effective for a range of gem-dichloro partners including those containing sulfur and nitrogen heterocycles. An example of an intramolecular Rh-catalyzed [5+2]-cycloaddition of a vinyl spirocyclopropane is demonstrated, providing rapid access to a complex tricyclic framework. Overall, this catalyst system is capable of suppressing the kinetically facile 1,2-hydride shift, which has hampered the development of Simmons?Smith reactions using Zn carbenoids possessing beta-hydrogen atoms. (Figure presented.).

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