Category: 2905-56-8

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.2905-56-8,1-Benzylpiperidine,as a common compound, the synthetic route is as follows.

In the reaction tube is sequentially added 1n (0.5 mmol, 88 mg), 2a (0.6 mmol, 90 mg), acetonitrile (3 ml), copper bromide (0.05 mmol, 11 mg) and di-tert-butyl peroxide (1 mmol, 183 mul), in air (1 atm) atmosphere at 60 C stirring reaction 24 h. Then add 10 ml saturated salt water quenching reaction, extracted with ethyl acetate (10 ml × 3), combined with the organic phase, dried with anhydrous sodium sulfate. Filtering, turns on lathe does, too separating by silica gel column (petroleum ether/ethyl acetate=5/1) to get the yellow solid product 3n (71 mg, 51%)., 2905-56-8

The synthetic route of 2905-56-8 has been constantly updated, and we look forward to future research findings.

Reference：
Patent; Henan Normal University; Fan Xuesen; Shi Xiaonan; Zhang Xinying; Chen Qian; (19 pag.)CN108516952; (2018); A;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem

2905-56-8, 1-Benzylpiperidine is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Oxidation of various tertiary amines using catalyst B was carried out following the procedure as in example 2 and the results are given in Table 2., 2905-56-8

2905-56-8 1-Benzylpiperidine 76190, apiperidines compound, is more and more widely used in various fields.

Reference：
Patent; Council of Scientific and Industrial Research; EP1348692; (2003); A1;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.2905-56-8,1-Benzylpiperidine,as a common compound, the synthetic route is as follows.

General procedure: To a suspension of 1-(chloromethyl)-4-fluoro-1,4-diazoniabicyclo[2.2.2]octane ditetrafluoroborate (1, 0.975 mmol) in MeCN(3 mL) the amine (2, 0.75 mmol) dissolved in MeCN (3 mL) was added dropwise at r.t. The reaction was stirred at r.t. for another20 min. The solvent was evaporated, and the obtained residuewas purified via flash column chromatography using silica gel as stationary phase. Benzaldehyde (5a) 1H NMR (400 MHz, CDCl3): delta = 10.05 (s, 1 H), 7.89?7.95 (m, 2 H),7.63?7.69 (m, 1 H), 7.54?7.60 (m, 2 H) ppm. 13C NMR (101 MHz,CDCl3): delta = 192.4, 136.5, 134.5, 129.8, 129.0 ppm. IR: nu = 3070(m), 2837 (m), 2678 (w), 1559 (w), 1686 (vs) cm?1., 2905-56-8

2905-56-8 1-Benzylpiperidine 76190, apiperidines compound, is more and more widely used in various fields.

Reference：
Article; Hauser, Anett; Bohlmann, Rolf; Synlett; vol. 27; 12; (2016); p. 1870 – 1872;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem