Category: 281652-10-6

Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent， category: piperidines, Which mentioned a new discovery about 281652-10-6

The invention, in a first aspect relates to compounds o f formula (I) or a pharmaceutically acceptable salt thereof, wherein R is a 6-membered aromatic ring, or a 5- or 6-membered heteroaromatic ring comprising 1 to 3 heteroatoms selected from S, O and N, or a 6-membered benzo condensed heteroaromatic ring containing N as heteroatom, optionally each of said rings being substituted with one or two substituents selected from the group consisting of (Cl-C3)alkyl, (C3-C5)cycloalkyloxy, (Cl-C3)alkylcarbonyl, cyano, trifluoromethyl, dimethylamino, or phenyl which optionally is substituted with one or more halogen atoms, or a 5- or 6-membered heterocycle containing from one to three nitrogen atoms; X is O or N; P is pyridyl, pyrimidyl, pyrazyl, or pyridazyl, each being optionally substituted with one or more substituents selected from the group consisting of (Cl-C3)alkyl, halogen, trifluoromethyl, and cyano, and use thereof as pharmaceuticals

Because enzymes can increase reaction rates by enormous factors and tend to be very specific, category: piperidines, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 281652-10-6

Reference：
Piperidine – Wikipedia,
Piperidine | C5H17890N – PubChem

 

Application of 281652-10-6, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.281652-10-6, Name is 1-Boc-4,4-difluoropiperidine, molecular formula is C10H17F2NO2. In a article£¬once mentioned of 281652-10-6

C-3 NOVEL TRITERPENONE WITH C-28 AMIDE DERIVATIVES AS HIV INHIBITORS

The invention relates to C-3 novel triterpenone with C-28 amide derivatives, related compounds, and pharmaceutical compositions useful for the therapeutic treatment of viral diseases and particularly HIV mediated diseases (formula 1).

We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 281652-10-6, and how the biochemistry of the body works.Application of 281652-10-6

Reference£º
Piperidine – Wikipedia,
Piperidine | C5H17892N – PubChem

 

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.281652-10-6,1-Boc-4,4-difluoropiperidine,as a common compound, the synthetic route is as follows.

Example A.13 Preparation of Intermediate (16).(tnfluoroacetate salt) TFA (2 mL, 26 mmol, 10 eq) was added under stirring to a solution of 1-N-boc- 4,4-difluoromethylpiperidine (0.53 g, 2.25 mmol) in DCM (8 mL), cooled with an icebath. The reaction mixture was allowed to warm at room temperature and stirred for additional 30 minutes. Solvent was removed at reduced pressure, affording 0.73 g (70% yield over two steps) of intermediate 16 as a TFA salt.

281652-10-6, As the paragraph descriping shows that 281652-10-6 is playing an increasingly important role.

Reference£º
Patent; AXXAM S.P.A.; PEVARELLO, Paolo; LOHMER, Stefan; LIBERATI, Chiara; SENECI, Pierfausto; PESENTI, Cristina; PRANDI, Adolfo; WO2015/118019; (2015); A1;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem