Category: 23794-15-2

The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 1-(2-chloropyridine-4-yl)ethanone(SMILESS: CC(=O)C1=CC(Cl)=NC=C1,cas:23794-15-2) is researched.Product Details of 3230-65-7. The article 《Iron-Catalyzed Arylation of Heterocycles via Directed C-H Bond Activation [Erratum to document cited in CA160:248695]》 in relation to this compound, is published in Organic Letters. Let’s take a look at the latest research on this compound (cas:23794-15-2).

On page 868, Scheme 1 contained inverted references; the corrected scheme is given. On page 870, the text accompanying Table 3 contained an incorrect substrate name; the correct substrate is 4-methylthiophene. On page 871, reference 6b contained misspelled names; the corrected reference is given.

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Reference:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Discovery of 8-azabicyclo[3.2.1]octan-3-yloxy-benzamides as selective antagonists of the kappa opioid receptor. Part 1, published in 2010-10-01, which mentions a compound: 23794-15-2, Name is 1-(2-chloropyridine-4-yl)ethanone, Molecular C7H6ClNO, Category: piperidines.

Initial high throughput screening efforts identified highly potent and selective kappa opioid receptor antagonist 3 (κ IC50 = 77 nM; μ:κ and δ:κ IC50 ratios >400) which lacked CNS exposure in vivo. Modification of this scaffold resulted in development of a series of 8-azabicyclo[3.2.1]octan-3-yloxy-benzamides showing potent and selectivity κ antagonism as well as good brain exposure. Analog 6c (I) (κ IC50 = 20 nM; μ:κ = 36, δ:κ = 415) was also shown to reverse κ-agonist induced rat diuresis in vivo.

There is still a lot of research devoted to this compound(SMILES：CC(=O)C1=CC(Cl)=NC=C1)Category: piperidines, and with the development of science, more effects of this compound(23794-15-2) can be discovered.

Reference:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Related Products of 23794-15-2. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: 1-(2-chloropyridine-4-yl)ethanone, is researched, Molecular C7H6ClNO, CAS is 23794-15-2, about Visible-Light Photocatalytic Difluoroalkylation-Induced 1, 2-Heteroarene Migration of Allylic Alcohols in Batch and Flow. Author is Wei, Xiao-Jing; Noel, Timothy.

A convenient method for the preparation of sp3-rich heterocycles is reported. The method comprises a photocatalytic difluoroalkylation-induced 1,2-heteroarene migration of allylic alcs. Here we describe for the first time the benefits of using flow to facilitate such migration reactions, including shorter reaction times, higher selectivities, and opportunities to scale the chem.

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Reference:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem