With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.19395-41-6,Ritalinic acid,as a common compound, the synthetic route is as follows.
Example 8 Conjugation of RA to BTG To a solution of RA (29.6mg, 0.135mmol) in DMF (1.0ml) was added N,N-dicyclohexylcarbodiimide (DCC) (31.0mg, 0.149mmol) and N-hydroxysuccinimide (17.13mg, 0.149mmol) and the mixture was stirred at room temperature overnight. The dicyclohexylurea formed was removed by filtration and the solution was added dropwise to a solution of BTG (150mg) in 50mM sodium bicarbonate solution (pH 8.5) (10ml)., 19395-41-6
19395-41-6 Ritalinic acid 86863, apiperidines compound, is more and more widely used in various fields.
Reference£º
Patent; Randox Laboratories Ltd.; Benchikh, Elouard; Fitzgerald, Peter; Lowry, Philip; McConnell, Ivan; EP2769994; (2014); A2;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem