Category: 1928-81-0

Synthesis of fused dihydropyrido[e]purines via ring closing metathesis was written by Litinas, Konstantinos E.;Thalassitis, Andreas. And the article was included in Tetrahedron Letters in 2010.Application In Synthesis of 6-(Piperidin-1-yl)-9H-purine This article mentions the following:

Ring closing metathesis (RCM) of 8,9-diallylpurines or 9-butenyl-8-vinylpurines with the Grubbs 2nd generation catalyst resulted in fused 6,9- or 8,9-dihydropyrido[e]purines, resp. The 8,9-dialkenylpurines were prepared from 8-bromopurines after 9-alkenylation and subsequent Stille coupling at C-8 with alkenylstannanes in the presence of Pd(PPh₃)₄ or Pd(PPh₃)₂Cl₂. In the experiment, the researchers used many compounds, for example, 6-(Piperidin-1-yl)-9H-purine (cas: 1928-81-0Application In Synthesis of 6-(Piperidin-1-yl)-9H-purine).

6-(Piperidin-1-yl)-9H-purine (cas: 1928-81-0) belongs to piperidine derivatives. The piperidine structural motif is present in numerous natural alkaloids. These include piperine, which gives black pepper its spicy taste. Several piperidine alkaloids isolated from natural herbs, were found to exhibit antiproliferation and antimetastatic effects on various types of cancers both in vitro and in vivo for example Piperine, Evodiamine, Matrine, Berberine and Tetrandine.Application In Synthesis of 6-(Piperidin-1-yl)-9H-purine

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Synthesis of Chiral Acyclic Nucleosides by Sharpless Asymmetric Dihydroxylation: Access to Cidofovir and Buciclovir was written by Qin, Tao;Li, Jian-Ping;Xie, Ming-Sheng;Qu, Gui-Rong;Guo, Hai-Ming. And the article was included in Journal of Organic Chemistry in 2018.Reference of 1928-81-0 This article mentions the following:

An efficient method to construct chiral acyclic nucleosides via Sharpless asym. dihydroxylation of N-allylpyrimidines or N-alkenylpurines is reported. A range of chiral acyclic nucleosides with two adjacent hydroxyl groups present on the side chains could be produced in good yields (up to 97% yield) and excellent enantioselectivities (90-99% ee). The synthetic utility of the reaction was demonstrated by the catalytic asym. synthesis of (S)-Cidofovir and (R)-Buciclovir. In the experiment, the researchers used many compounds, for example, 6-(Piperidin-1-yl)-9H-purine (cas: 1928-81-0Reference of 1928-81-0).

6-(Piperidin-1-yl)-9H-purine (cas: 1928-81-0) belongs to piperidine derivatives. Piperidine is a metabolite of cadaverine, a polyamine found in the human intestine. Several piperidine alkaloids isolated from natural herbs, were found to exhibit antiproliferation and antimetastatic effects on various types of cancers both in vitro and in vivo for example Piperine, Evodiamine, Matrine, Berberine and Tetrandine.Reference of 1928-81-0

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Effect of solvents on the fluorescence characteristics of 6-anilinopurine and 6-piperidinopurine was written by Abdullah, Zanariah;Bakar, Maizathul Akmam A.;Mohd Shariffuddin, Mohd Adlan;Aiyub, Zaharah. And the article was included in Journal of Ultra Chemistry in 2006.Application of 1928-81-0 This article mentions the following:

6-Chloropurine which was obtained com. was used as the precursor for the preparation of 6-anilinopurine and of 6-piperidinopurine. Fluorescence studies were carried out in 75% ethanol, acetonitrile and Et acetate. Both compounds showed the highest fluorescence peak in Et acetate whereby 6-piperidinopurine showed fluorescence peak at 373 nm, when excited at 315 nm, and 6-anilinopurine showed fluorescence peak at 447 nm when excited at 321 nm. The fluorescence intensity of 6-anilinopurine and 6-piperidinopurine decreased with time. In the experiment, the researchers used many compounds, for example, 6-(Piperidin-1-yl)-9H-purine (cas: 1928-81-0Application of 1928-81-0).

6-(Piperidin-1-yl)-9H-purine (cas: 1928-81-0) belongs to piperidine derivatives. Piperidine is a metabolite of cadaverine, a polyamine found in the human intestine. Piperidine prefers a chair conformation, similar to cyclohexane. Unlike cyclohexane, piperidine has two distinguishable chair conformations: one with the N鈥揌 bond in an axial position, and the other in an equatorial position.Application of 1928-81-0

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Synthesis of Chiral Acyclic Nucleosides by Sharpless Asymmetric Dihydroxylation: Access to Cidofovir and Buciclovir was written by Qin, Tao;Li, Jian-Ping;Xie, Ming-Sheng;Qu, Gui-Rong;Guo, Hai-Ming. And the article was included in Journal of Organic Chemistry in 2018.Reference of 1928-81-0 This article mentions the following:

An efficient method to construct chiral acyclic nucleosides via Sharpless asym. dihydroxylation of N-allylpyrimidines or N-alkenylpurines is reported. A range of chiral acyclic nucleosides with two adjacent hydroxyl groups present on the side chains could be produced in good yields (up to 97% yield) and excellent enantioselectivities (90-99% ee). The synthetic utility of the reaction was demonstrated by the catalytic asym. synthesis of (S)-Cidofovir and (R)-Buciclovir. In the experiment, the researchers used many compounds, for example, 6-(Piperidin-1-yl)-9H-purine (cas: 1928-81-0Reference of 1928-81-0).

6-(Piperidin-1-yl)-9H-purine (cas: 1928-81-0) belongs to piperidine derivatives. Piperidine is a metabolite of cadaverine, a polyamine found in the human intestine. Several piperidine alkaloids isolated from natural herbs, were found to exhibit antiproliferation and antimetastatic effects on various types of cancers both in vitro and in vivo for example Piperine, Evodiamine, Matrine, Berberine and Tetrandine.Reference of 1928-81-0

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Effect of solvents on the fluorescence characteristics of 6-anilinopurine and 6-piperidinopurine was written by Abdullah, Zanariah;Bakar, Maizathul Akmam A.;Mohd Shariffuddin, Mohd Adlan;Aiyub, Zaharah. And the article was included in Journal of Ultra Chemistry in 2006.Application of 1928-81-0 This article mentions the following:

6-Chloropurine which was obtained com. was used as the precursor for the preparation of 6-anilinopurine and of 6-piperidinopurine. Fluorescence studies were carried out in 75% ethanol, acetonitrile and Et acetate. Both compounds showed the highest fluorescence peak in Et acetate whereby 6-piperidinopurine showed fluorescence peak at 373 nm, when excited at 315 nm, and 6-anilinopurine showed fluorescence peak at 447 nm when excited at 321 nm. The fluorescence intensity of 6-anilinopurine and 6-piperidinopurine decreased with time. In the experiment, the researchers used many compounds, for example, 6-(Piperidin-1-yl)-9H-purine (cas: 1928-81-0Application of 1928-81-0).

6-(Piperidin-1-yl)-9H-purine (cas: 1928-81-0) belongs to piperidine derivatives. Piperidine is a metabolite of cadaverine, a polyamine found in the human intestine. Piperidine prefers a chair conformation, similar to cyclohexane. Unlike cyclohexane, piperidine has two distinguishable chair conformations: one with the N–H bond in an axial position, and the other in an equatorial position.Application of 1928-81-0

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem