Brief introduction of 18650-39-0

18650-39-0 Methyl (S)-piperidine-2-carboxylate hydrochloride 13246232, apiperidines compound, is more and more widely used in various.

18650-39-0, Methyl (S)-piperidine-2-carboxylate hydrochloride is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

[()-L-PYRIDIN-2-YLMETHYL-PIPERIDINE-2-CARBOXYLIC] acid methyl ester (2.25 g, 100percent) was obtained as described in Example 14 from [(59-METHYL] pipecolinate hydrochloride (1.68 g, 9.37 mmol) reacted with pyridine-2-carbaldehyde (1.0 g, 9.37 mmol) and sodium triacetoxyborohydride (2. 78 g, 13.1 mmol) in triethylamine (946 mg, 9.37 mmol) in dichloroethane (20 mL) at room [TEMPERATURE. LH NMR (CDC13), 6] (ppm): 8.53 (d, 1H), 7.65 (td, 1H), 7.49 (d, 1H), 7.14 (t, 1H), 3. 89 (d, 1H), 3.73 (s, 3H), 3.68 (d, 1H), 3.25 (dd, 1H), 2.97 (m, 1H), 2.25 (m, 1H), 1. 85 (m, 2H), 1.30-1. 76 (m, 4H).

18650-39-0 Methyl (S)-piperidine-2-carboxylate hydrochloride 13246232, apiperidines compound, is more and more widely used in various.

Reference£º
Patent; ASTRAZENECA AB; NPS PHARMACEUTICALS, INC.; WO2004/14902; (2004); A2;,
Piperidine – Wikipedia
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