Category: 14691-89-5

Chemistry is an experimental science, Safety of 4-Acetamido-2,2,6,6-tetramethylpiperidine 1-oxyl, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 14691-89-5, Name is 4-Acetamido-2,2,6,6-tetramethylpiperidine 1-oxyl, molecular formula is C11H21N2O2*, belongs to piperidines compound. In a document, author is Nakhate, Akhil V..

Cu2O nanoparticles supported hydrothermal carbon microspheres as catalyst for propargylamine synthesis

Cu2O nanoparticles supported on hydrothermal carbon microsphere (HTC) have been synthesized by hydro thermal synthesis followed by chemical reduction method. The prepared catalyst was used for propargylamine synthesis from the coupling of phenyl acetylene with benzaldehyde and piperidine. In this protocol, biomass derived D-glucose was used as carbon source for the synthesis of carbon microspheres by hydrothermal treatment and CuCl2 center dot 6H(2)O as a copper precursor. The activity of Cu2O@HTC was compared with different catalysts such as CuFe2O4, CuCl2 center dot 2H(2)O, commercial CuO, and Cu2O. Among them Cu2O@HTC exhibited the best activity and selectivity for propargylamine synthesis. The catalyst was well characterized by several analytical techniques such as SEM, XRD, FTIR, TEM, ICP-AES, and XPS analysis before and after 5th reuse. The effect of various parameters was studied including solvent, catalyst loading, mole ratio and temperature of the reaction to achieve the best yield at 60 degrees C and 1.5 x 10 (-3)g/cm(3) catalyst loading. Notably, Cu2O@HTC was recycled five times and found to be robust.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 14691-89-5, in my other articles. Safety of 4-Acetamido-2,2,6,6-tetramethylpiperidine 1-oxyl.

Reference:
Piperidine – Wikipedia,
,Piperidine | C5H11N – PubChem

 

Chemistry can be defined as the study of matter and the changes it undergoes. You¡¯ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology. 14691-89-5, Name is 4-Acetamido-2,2,6,6-tetramethylpiperidine 1-oxyl, molecular formula is , belongs to piperidines compound. In a document, author is de Oliveira, Isadora M., Formula: C11H21N2O2*.

Copper(I)/succinic acid cooperatively catalyzed one-pot synthesis of organoselenium-propargylamines via A(3)-coupling

Selenium propargylamines were synthesized via an A(3)-coupling approach using piperidine, p-methoxybenzaldehyde, and trimethylsilyl selenium-acetylene, catalyzed by copper(i) chloride and succinic acid as an additive, in good to excellent yields. This method is advantageous in that desilylation of the trimethylsilyl selenium-acetylene occurs in situ. The reaction time was monitored by FTIR studies and a probable mechanism is described. Scale-up was also performed in satisfactory yield. These selenium propargylamines could be hydrohalogenated to synthesize halovinyl selenides. The stereochemistry was determined by treatment with n-butyllithium and the coupling constant (J) values in H-1 NMR spectra. The vinyl selenides were employed in Sonogashira cross-coupling reactions to produce the corresponding enynes, with yields ranging from moderate to good.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 14691-89-5, in my other articles. Formula: C11H21N2O2*.

Reference:
Piperidine – Wikipedia,
,Piperidine | C5H11N – PubChem

 

Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, 14691-89-5, Name is 4-Acetamido-2,2,6,6-tetramethylpiperidine 1-oxyl, SMILES is CC1(C)CC(NC(C)=O)CC(C)(C)N1[O], belongs to piperidines compound. In a document, author is Aziz-ur-Rehman, introduce the new discover, Application In Synthesis of 4-Acetamido-2,2,6,6-tetramethylpiperidine 1-oxyl.

Synthesis of some new propanamide derivatives bearing 4-piperidinyl-1,3,4-oxadiazole, and their evaluation as promising anticancer agents

Purpose: To sequentially synthesize piperidine-4-carboxylic acid ethyl ester-appended 1,3,4-oxadiazole hybrids and to evaluate them as anticancer agents. Methods: Ethyl 1-[(4-methylphenyl)sulfonyl]-4-piperidinecarboxylate (1) was synthesized from 4-methylbenzenesulfonylchloride (a) and ethyl 4-piperidinecarboxylate (b) Compound (1) was converted into ethyl 1-[(4-methylphenyl)sulfonyl]-4-piperidine carbohydrazides (2) and 5-{1-[(4-methylphenyl)sulfonyl]-4-piperidinyl}-1,3,4-oxadiazole-2-thiol (3) respectively. A variety of aryl amine (4a-l) were treated with 2-bromopropionylbromide to synthesize an array of propanamide (5a-l). Finally, 5-{1-[(4-methylphenyl)sulfonyl]-4-piperidinyl}-1,3,4-oxadiazole-2-thiol (3) and propanamides (5a-l) were reacted to synthesize target compounds (6a-l) Purity compounds 6a-l was confirmed by spectroscopic techniques like (H-1-NMR), (C-13-NMR) and EI-MS. To determine their anticancer potential, the change in absorbance of mixture and cell line before and after incubation was determined Results: All the compounds 6a-l were successfully synthesized in 73-85 % yield. Compounds 6h, 6j and 6e have low ICso (+/- SD) values of 20 12 +/- 6 20, 10 84 +/- 4 2 and 24 57 +/- 1.62 mu M to act as strong anticancer agents relative to doxorubicin (0.92 +/- 0.1 mu M) used as a reference. Conclusion: The synthesized propanamide derivatives bearing 4-piperidinyl-1,3,4-oxadiazole are potential anticancer agents, but further studies, especially in vivo, are required to ascertain their therapeutic usefulness.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 14691-89-5 is helpful to your research. Application In Synthesis of 4-Acetamido-2,2,6,6-tetramethylpiperidine 1-oxyl.

Reference:
Piperidine – Wikipedia,
,Piperidine | C5H11N – PubChem