Category: 1445-73-4

The author of 《Highly durable and conductive poly(arylene piperidine) with a long heterocyclic ammonium side-chain for hydroxide exchange membranes》 were Jin, Cuihong; Zhang, Shuai; Cong, Yuanyuan; Zhu, Xiuling. And the article was published in International Journal of Hydrogen Energy in 2019. Related Products of 1445-73-4 The author mentioned the following in the article:

Recently, the preparation of hydroxide exchange membranes (HEMs) without ether bonds have attracted much attention because of their high chem. stability. Hence, ether-bond free, highly durable, and conductive poly(arylene piperidine)s (PAPips) tethered with heterocyclic ammonium via hexyl spacer chains were prepared successfully for HEMs via a facile synthetic procedure. The effect of the cationic groups (quaternary ammonium, piperidinium, and morpholinium) on the properties of the corresponding PAPip-based HEMs, including the morphol., hydroxide conductivity, and alk. and chem. stability were systematically investigated. The as-designed PAPip-based membranes exhibited excellent overall performance. The membranes attached with piperidinium (IEC = 1.64 mmol g-1) exhibited a hydroxide conductivity of 0.082 S cm-1 at 80°C and exhibited significant alk. stability which maintained 80.1% of its conductivity after immersion in 1 M NaOH at 80°C for 1500 h. The as-prepared membrane also presented a peak power d. of 76 mW cm-2 at 80°C in a H2/O2 HEMFC. The resulting HEMs also showed excellent mech. properties, thermal stability, and well-defined phase separation In the experimental materials used by the author, we found 1-Methyl-4-piperidone(cas: 1445-73-4Related Products of 1445-73-4)

1-Methyl-4-piperidone(cas: 1445-73-4) is a member of piperidine. Piperidine-containing compounds are also frequently employed in synthesis as ligands or auxiliaries. Accordingly, many efforts have been devoted to the development of novel methods for the synthesis of these compounds over the years.Related Products of 1445-73-4

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Chen, Nanjun; Hu, Chuan; Wang, Ho Hyun; Kim, Sun Pyo; Kim, Hae Min; Lee, Won Hee; Bae, Joon Yong; Park, Jong Hyeong; Lee, Young Moo published an article in 2021. The article was titled 《Poly(Alkyl-Terphenyl Piperidinium) Ionomers and Membranes with an Outstanding Alkaline-Membrane Fuel-Cell Performance of 2.58 W cm-2》, and you may find the article in Angewandte Chemie, International Edition.Recommanded Product: 1-Methyl-4-piperidone The information in the text is summarized as follows:

Aryl-ether-free anion-exchange ionomers (AEIs) and membranes (AEMs) have become an important benchmark to address the insufficient durability and power-d. issues associated with AEM fuel cells (AEMFCs). Here, we present aliphatic chain-containing poly(diphenyl-terphenyl piperidinium) (PDTP) copolymers to reduce the Ph content and adsorption of AEIs and to increase the mech. properties of AEMs. Specifically, PDTP AEMs possess excellent mech. properties (storage modulus>1800 MPa, tensile strength>70 MPa), H2 fuel-barrier properties (<10 Barrer), good ion conductivity, and ex-situ stability. Meanwhile, PDTP AEIs with low Ph content and high-water permeability display excellent peak power densities (PPDs). The present AEMFCs reach outstanding PPDs of 2.58 W cm-2(>7.6 A cm-2c.d.) and 1.38 W cm-2 at 80°C in H2/O2 and H2/air, resp., along with a specific power (PPD/catalyst loading) over 8 W mg-1, which is the highest record for Pt-based AEMFCs so far. In addition to this study using 1-Methyl-4-piperidone, there are many other studies that have used 1-Methyl-4-piperidone(cas: 1445-73-4Recommanded Product: 1-Methyl-4-piperidone) was used in this study.

1-Methyl-4-piperidone(cas: 1445-73-4) is a member of piperidine. Piperidine-containing compounds are also frequently employed in synthesis as ligands or auxiliaries. Accordingly, many efforts have been devoted to the development of novel methods for the synthesis of these compounds over the years.Recommanded Product: 1-Methyl-4-piperidone

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

In 2022,Lu, Shaoyong; Fu, Zhong; Li, Fu; Weng, Kangkang; Zhou, Likuan; Zhang, Lipeng; Yang, Yuchen; Qiu, Hengwei; Liu, Dan; Qing, Wenyue; Ding, He; Sheng, Xing; Chen, Menglu; Tang, Xin; Duan, Lian; Liu, Wenyong; Wu, Longjia; Yang, Yixing; Zhang, Hao; Li, Jinghong published an article in Angewandte Chemie, International Edition. The title of the article was 《Beyond a Linker: The Role of Photochemistry of Crosslinkers in the Direct Optical Patterning of Colloidal Nanocrystals》.Electric Literature of C6H11NO The author mentioned the following in the article:

Surface chem. mediated direct optical patterning represents an emerging strategy for incorporating colloidal nanocrystals (NCs) in integrated optoelectronic platforms including displays and image sensors. However, the role of photochem. of crosslinkers and other photoactive species in patterning remains elusive. Here we show the design of nitrene- and carbene-based photocrosslinkers can strongly affect the patterning capabilities and photophys. properties of NCs, especially quantum dots (QDs). Their role beyond phys. linkers stems from structure-dictated electronic configuration, energy alignment and associated reaction kinetics and thermodn. Patterned QD layers with designed carbene-based crosslinkers fully preserve their photoluminescent and electroluminescent properties. Patterned light emitting diodes (QLEDs) show a maximum external quantum efficiency of ∼12 % and lifetime over 4800 h, among the highest for reported patterned QLEDs. These results would guide the rational design of photoactive species in NC patterning and create new possibilities in the monolithic integration of NCs in high-performance device platforms. The experimental part of the paper was very detailed, including the reaction process of 1-Methyl-4-piperidone(cas: 1445-73-4Electric Literature of C6H11NO)

1-Methyl-4-piperidone(cas: 1445-73-4) is a member of piperidine. Piperidine is ubiquitous structural motif widely occurred in diverse synthetically and naturally occurring bioactive molecules. Piperidines are an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.Electric Literature of C6H11NO

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Chen, Nanjun; Hu, Chuan; Wang, Ho Hyun; Kim, Sun Pyo; Kim, Hae Min; Lee, Won Hee; Bae, Joon Yong; Park, Jong Hyeong; Lee, Young Moo published an article in 2021. The article was titled 《Poly(Alkyl-Terphenyl Piperidinium) Ionomers and Membranes with an Outstanding Alkaline-Membrane Fuel-Cell Performance of 2.58 W cm-2》, and you may find the article in Angewandte Chemie, International Edition.Recommanded Product: 1-Methyl-4-piperidone The information in the text is summarized as follows:

Aryl-ether-free anion-exchange ionomers (AEIs) and membranes (AEMs) have become an important benchmark to address the insufficient durability and power-d. issues associated with AEM fuel cells (AEMFCs). Here, we present aliphatic chain-containing poly(diphenyl-terphenyl piperidinium) (PDTP) copolymers to reduce the Ph content and adsorption of AEIs and to increase the mech. properties of AEMs. Specifically, PDTP AEMs possess excellent mech. properties (storage modulus>1800 MPa, tensile strength>70 MPa), H2 fuel-barrier properties (<10 Barrer), good ion conductivity, and ex-situ stability. Meanwhile, PDTP AEIs with low Ph content and high-water permeability display excellent peak power densities (PPDs). The present AEMFCs reach outstanding PPDs of 2.58 W cm-2(>7.6 A cm-2c.d.) and 1.38 W cm-2 at 80°C in H2/O2 and H2/air, resp., along with a specific power (PPD/catalyst loading) over 8 W mg-1, which is the highest record for Pt-based AEMFCs so far. In addition to this study using 1-Methyl-4-piperidone, there are many other studies that have used 1-Methyl-4-piperidone(cas: 1445-73-4Recommanded Product: 1-Methyl-4-piperidone) was used in this study.

1-Methyl-4-piperidone(cas: 1445-73-4) is a member of piperidine. Piperidine-containing compounds are also frequently employed in synthesis as ligands or auxiliaries. Accordingly, many efforts have been devoted to the development of novel methods for the synthesis of these compounds over the years.Recommanded Product: 1-Methyl-4-piperidone

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

In 2022,Lu, Shaoyong; Fu, Zhong; Li, Fu; Weng, Kangkang; Zhou, Likuan; Zhang, Lipeng; Yang, Yuchen; Qiu, Hengwei; Liu, Dan; Qing, Wenyue; Ding, He; Sheng, Xing; Chen, Menglu; Tang, Xin; Duan, Lian; Liu, Wenyong; Wu, Longjia; Yang, Yixing; Zhang, Hao; Li, Jinghong published an article in Angewandte Chemie, International Edition. The title of the article was 《Beyond a Linker: The Role of Photochemistry of Crosslinkers in the Direct Optical Patterning of Colloidal Nanocrystals》.Electric Literature of C6H11NO The author mentioned the following in the article:

Surface chem. mediated direct optical patterning represents an emerging strategy for incorporating colloidal nanocrystals (NCs) in integrated optoelectronic platforms including displays and image sensors. However, the role of photochem. of crosslinkers and other photoactive species in patterning remains elusive. Here we show the design of nitrene- and carbene-based photocrosslinkers can strongly affect the patterning capabilities and photophys. properties of NCs, especially quantum dots (QDs). Their role beyond phys. linkers stems from structure-dictated electronic configuration, energy alignment and associated reaction kinetics and thermodn. Patterned QD layers with designed carbene-based crosslinkers fully preserve their photoluminescent and electroluminescent properties. Patterned light emitting diodes (QLEDs) show a maximum external quantum efficiency of ∼12 % and lifetime over 4800 h, among the highest for reported patterned QLEDs. These results would guide the rational design of photoactive species in NC patterning and create new possibilities in the monolithic integration of NCs in high-performance device platforms. The experimental part of the paper was very detailed, including the reaction process of 1-Methyl-4-piperidone(cas: 1445-73-4Electric Literature of C6H11NO)

1-Methyl-4-piperidone(cas: 1445-73-4) is a member of piperidine. Piperidine is ubiquitous structural motif widely occurred in diverse synthetically and naturally occurring bioactive molecules. Piperidines are an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.Electric Literature of C6H11NO

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

HPLC of Formula: 1445-73-4In 2019 ,《Protein labelling and albumin binding characteristics of the near-IR Cy7 fluorophore, QuatCy》 appeared in Organic & Biomolecular Chemistry. The author of the article were Thavornpradit, Sopida; Usama, Syed Muhammad; Lin, Chen-Ming; Burgess, Kevin. The article conveys some information:

Free cysteine residues react with QuatCy 1, by simply mixing the protein and dye in aqueous buffer at 37°C. Another dye, MHI-148, can be used for a similar labeling protocol, but QuatCy reacts faster with all proteins studied, except albumin; it emerges here that this is because MHI-148 instantly forms of a non-covalent complex with albumin, but QuatCy does not. Labeling with QuatCy has advantages insofar as it is over five times brighter, and much more photostable, than MHI-148, and combination labeling with this dye pair will allow multiplexing in the near-IR region. In the experimental materials used by the author, we found 1-Methyl-4-piperidone(cas: 1445-73-4HPLC of Formula: 1445-73-4)

1-Methyl-4-piperidone(cas: 1445-73-4) is a member of piperidine. Piperidine is a key saturated heterocyclic scaffold found in several of the top-selling small molecule pharmaceuticals and natural alkaloids, with a diverse range of biological activities. Hence, continuous efforts have been made to develop convenient methods to prepare piperidine derivatives.HPLC of Formula: 1445-73-4

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

《New access to pyrano[2,3-c]pyrazole-3-carboxylates via domino four-component reaction and their antimicrobial activity》 was written by Maarop, Muhammad Siddiq; Rashid, Fatin Nur Ain Abdul; Mohammat, Mohd Fazli; Shaameri, Zurina; Johari, Saiful Azmi; Isa, Mazurah Mohamed; Low, Anis Muhammad. SDS of cas: 1445-73-4 And the article was included in Indonesian Journal of Chemistry in 2020. The article conveys some information:

A library of some novel classes of pyrano[2,3-c]pyrazole-3-carboxylates I [R = Et, i-Pr, Ph, etc.] was synthesized by employing uncatalyzed domino four-component reaction using diethyloxaloacetate, hydrazine hydrate, aldehydes and malononitrile in refluxing of ethanol-acetic acid solvent systems. Series of domino reactions involving of pyrazolone formation, Michael addition, and Thorpe-Ziegler cyclization reaction managed to produce the cyclized products I from moderate to excellent yield. This protocol provided a reliable, general and salient procedure for the title compound I using a one-pot approach. Preliminary biol. screening unveiled limited potentials of this class of compounds I for antimicrobial lead compound due to its limited solubility properties. The experimental process involved the reaction of 1-Methyl-4-piperidone(cas: 1445-73-4SDS of cas: 1445-73-4)

1-Methyl-4-piperidone(cas: 1445-73-4) is a member of piperidine. Piperidine is ubiquitous structural motif widely occurred in diverse synthetically and naturally occurring bioactive molecules. Piperidines are an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.SDS of cas: 1445-73-4

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

《A divergent procedure for multicomponent synthesis of novel ferrocenyl derivatives of dicyanoanilines and cyanopyridines》 was written by Mojtahedi, Mohammad M.; Hosseinkhany, Samaneh; Abaee, M. Saeed; Mesbah, A. Wahid. Quality Control of 1-Methyl-4-piperidone And the article was included in Applied Organometallic Chemistry in 2020. The article conveys some information:

A divergent procedure was developed for multicomponent reaction of ferrocenecarboxaldehyde with malononitrile and various cyclic ketones. Ultrasonic irradiation of 1.0:1.0:2.0 ethanolic mixtures of the reactants produced dicyanoanilines, e.g. I, chemoselectively in high yields, while equimolar mixtures of the same reactants in refluxing EtOH solely resulted in four-component formation of cyanopyridines, e.g. II. Both series of products are obtained directly by spontaneous precipitation in the reaction mixtures avoiding cumbersome and expensive chromatog. separations In the experimental materials used by the author, we found 1-Methyl-4-piperidone(cas: 1445-73-4Quality Control of 1-Methyl-4-piperidone)

1-Methyl-4-piperidone(cas: 1445-73-4) is a member of piperidine. Piperidine is ubiquitous structural motif widely occurred in diverse synthetically and naturally occurring bioactive molecules. Piperidines are an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.Quality Control of 1-Methyl-4-piperidone

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Wang, Liujiao; You, Rixin; Ling, Yuxuan; Xie, Yu; Mei, Cenyu; Li, Ziming; Wang, Fanghui published an article in 2021. The article was titled 《Covalent cross-linked anion exchange membrane based on poly(biphenyl piperidine) and poly(styrene-b-(ethylene-co-butylene)-b-styrene): preparation and properties》, and you may find the article in Polymer-Plastics Technology and Materials.Computed Properties of C6H11NO The information in the text is summarized as follows:

Poly(biphenyl piperidine) and polystyrene-b-poly(ethylene-co-butylene)-b-polystyrene were cross-linked to form a polymer backbone, piperidine as the ionic conducting group to improve the chem. stability of the anion exchange membrane. Results indicate that the cross-linked membranes could still retain more than 95% of ion conductivity after being soaked in 1-M KOH solution at 80°C for 800 h, indicating that this cross-linked membrane exhibits good alk. stability. The optimized microphase separation morphol. could promote the ion transport (81.68 mS/cm, 80°C). The cross-linked structure helped to restrain the swelling behavior. The membrane became flexible after crosslinking, which is beneficial to the fuel-cell assembly. In the part of experimental materials, we found many familiar compounds, such as 1-Methyl-4-piperidone(cas: 1445-73-4Computed Properties of C6H11NO)

1-Methyl-4-piperidone(cas: 1445-73-4) is a member of piperidine. Piperidine-containing compounds are also frequently employed in synthesis as ligands or auxiliaries. Accordingly, many efforts have been devoted to the development of novel methods for the synthesis of these compounds over the years.Computed Properties of C6H11NO

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

《N-Benzyl-4,4-disubstituted piperidines as a potent class of influenza H1N1 virus inhibitors showing a novel mechanism of hemagglutinin fusion peptide interaction》 was published in European Journal of Medicinal Chemistry in 2020. These research results belong to de Castro, Sonia; Ginex, Tiziana; Vanderlinden, Evelien; Laporte, Manon; Stevaert, Annelies; Cumella, Jose; Gago, Federico; Camarasa, Maria Jose; Luque, F. Javier; Naesens, Lieve; Velazquez, Sonsoles. Safety of 1-Methyl-4-piperidone The article mentions the following:

Herein, N-benzyl-4,4,-disubstituted piperidines I (R1 = H, Me, cyclohexyl, Ph, PhCH2, PhCH2CH2; R2 = t-Bu, cyclohexyl, PhCH2, 4-MeC6H4SO2CH2; R3 = H, Me, cyclopropyl, PhCH2, 4-FC6H4CH2, etc.; R4 = Me, MeO2CCH2, PhCH2, etc.; R5 = H, Boc, Cbz) have been designed, synthesized and identified as influenza A virus fusion inhibitors with specific activity against the H1N1 subtype. A diverse library of piperidines I was synthesized using the highly efficient one-step Ugi four-component reaction. Mechanistic studies, including resistance selection with the most active compound I [R1 = R2 = PhCH2; R3 = 4-FC6H4CH2; R4 = MeO2CCH2; R5 = Boc; (II)], demonstrated that it acts as an inhibitor of the low pH-induced HA-mediated membrane fusion process. Computational studies identified an as yet unrecognized fusion inhibitor binding site, which is located at the bottom of the HA2 stem in close proximity to the fusion peptide. A direct π-stacking interaction between the N-benzylpiperidine moiety of the compound II and F9HA2 of the fusion peptide, reinforced with an addnl. π-stacking interaction with Y119HA2, and a salt bridge of the protonated piperidine nitrogen with E120HA2, were identified as important interactions to mediate ligand binding. This site rationalized the observed SAR and provided a structural explanation for the H1N1-specific activity of our inhibitors. Furthermore, the HA1-S326V mutation resulted in resistance to II was close to the proposed new binding pocket. These findings point to the N-benzyl-4,4-disubstituted piperidines as an interesting class of influenza virus inhibitors and represent the first example of fusion peptide binders with great potential for anti-influenza drug development. In the experimental materials used by the author, we found 1-Methyl-4-piperidone(cas: 1445-73-4Safety of 1-Methyl-4-piperidone)

1-Methyl-4-piperidone(cas: 1445-73-4) is a member of piperidine. Piperidine is a key saturated heterocyclic scaffold found in several of the top-selling small molecule pharmaceuticals and natural alkaloids, with a diverse range of biological activities. Hence, continuous efforts have been made to develop convenient methods to prepare piperidine derivatives.Safety of 1-Methyl-4-piperidone

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem