Category: 1445-73-4

Recommanded Product: 1-Methyl-4-piperidoneIn 2019 ,《Cocrystals and Salts of 3,5-Bis(pyridinylmethylene)piperidin-4-one with Aromatic Poly-Carboxylates and Resorcinols: Influence of Stacking Interactions on Solid-State Luminescence Properties》 appeared in Australian Journal of Chemistry. The author of the article were Das, Debarati; Biradha, Kumar. The article conveys some information:

Two bis-pyridyl-substituted α,β-unsaturated ketones form complexes with carboxylic acids and resorcinol derivatives The neutral acid-acid homosynthon was observed in only one complex out of the five acid-bis-pyridyl containing complexes studied here, while the -COO-···HOOC- synthon is dominant as it was observed in four complexes. The carboxylates self-assembled to form discrete dimeric, anionic, 1-dimensional chains and also exhibited mixed ionic H bonds. However, resorcinol derivatives displayed O-H···N H bonding to form tetrameric aggregates of bis-pyridyl ketone mols. and resp. co-formers, while 3,5-dihydroxy HOBz (DHBA) mols. formed 1-dimensional chains by clipping two mols. of ketones with three DHBA mols. Such clipping by the resorcinol derivatives promoted continuous π-π stacking interactions. Consequently, these materials emitted at higher wavelengths compared with the parent bis-pyridyl-substituted α,β-unsaturated ketones. After reading the article, we found that the author used 1-Methyl-4-piperidone(cas: 1445-73-4Recommanded Product: 1-Methyl-4-piperidone)

1-Methyl-4-piperidone(cas: 1445-73-4) is a member of piperidine. Piperidine-containing compounds are also frequently employed in synthesis as ligands or auxiliaries. Accordingly, many efforts have been devoted to the development of novel methods for the synthesis of these compounds over the years.Recommanded Product: 1-Methyl-4-piperidone

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

In 2019,Inorganica Chimica Acta included an article by Prishchenko, Andrey A.; Alekseyev, Roman S.; Livantsov, Mikhail V.; Novikova, Olga P.; Livantsova, Ludmila I.; Petrosyan, Valery S.. Safety of 1-Methyl-4-piperidone. The article was titled 《Bis(trimethylsiloxy)phosphine as key synthon for synthesis of new aminomethylphosphinic acids with N-alkyl 4-hydroxypiperidines moieties》. The information in the text is summarized as follows:

The convenient synthesis of new aminomethylphosphinic acids and their derivatives containing N-alkyl 4-hydroxypiperidines moieties was developed. The addition of bis(trimethylsiloxy)phosphine to N-alkyl 4-piperidones proceeds under mild conditions to give PH-phosphinates as key compounds for preparation of trimethylsilyl esters of above acids via interaction with various aminals. The further treatment of phosphinic acids trimethylsilyl esters with the methanol resulted in the water-soluble corresponding acids. The structures of aminomethylphosphinic acids and their precursors 1-3 with substituted piperidine moieties were confirmed by the 1H, 13C, 31P NMR spectra. In the experimental materials used by the author, we found 1-Methyl-4-piperidone(cas: 1445-73-4Safety of 1-Methyl-4-piperidone)

1-Methyl-4-piperidone(cas: 1445-73-4) is a member of piperidine. Piperidine is ubiquitous structural motif widely occurred in diverse synthetically and naturally occurring bioactive molecules. Piperidines are an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.Safety of 1-Methyl-4-piperidone

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

《Poly(meta/para-terphenylene-methyl piperidinium)-based anion exchange membranes: the effect of backbone structure in AEMFC application》 was written by Mayadevi, T. S.; Sung, Seounghwa; Varghese, Listo; Kim, Tae-Hyun. Synthetic Route of C6H11NO And the article was included in Membranes (Basel, Switzerland) in 2020. The article conveys some information:

A series of poly( meta/para-terphenylene-Me piperidinium)-based anion exchange membranes devoid of benzylic sites or aryl ether bonds, that are vulnerable to degradation by hydroxide ions, are synthesized and investigated for their application as novel anion exchange membranes. The copolymers are composed of both linear para-terphenyl units and kink-structured meta-terphenyl units. The meta-connectivity in terphenyl units permits the polymer backbones to fold back, maximizing the interactions among the hydrocarbon polymer chains and enhancing the peripheral formation of ion aggregates, due to the free volume generated by the kink structure. The effects of the copolymer composition between para-terphenyl and meta-terphenyl on the morphol. and the electrochem. and physicochem. properties of the corresponding polymer membranes are investigated. In the experiment, the researchers used 1-Methyl-4-piperidone(cas: 1445-73-4Synthetic Route of C6H11NO)

1-Methyl-4-piperidone(cas: 1445-73-4) is a member of piperidine. Piperidine is a key saturated heterocyclic scaffold found in several of the top-selling small molecule pharmaceuticals and natural alkaloids, with a diverse range of biological activities. Hence, continuous efforts have been made to develop convenient methods to prepare piperidine derivatives.Synthetic Route of C6H11NO

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Frolov, Andriy I.; Ostapchuk, Eugeniy N.; Pashenko, Alexander E.; Chuchvera, Yaroslav O.; Rusanov, Eduard B.; Volochnyuk, Dmitriy M.; Ryabukhin, Sergey V. published an article in 2021. The article was titled 《Selective α-Methylation of Ketones》, and you may find the article in Journal of Organic Chemistry.Reference of 1-Methyl-4-piperidone The information in the text is summarized as follows:

The convenient and scalable preparative approach for the two-step α-methylation of ketones was described. The optimized protocols for regioselective preparation of enaminones with further diastereoselective and functional groups tolerant hydrogenation to α-methylketones was developed. The scope and limitations of the proposed methodol. were discussed. The advantages compared to known procedures were demonstrated. The unexpected role of acetone in the hydrogenation was suggested. The evaluation of the method for both early building block synthesis and late-stage CH-functionalization was shown. The elaborate procedures preparability and scalability were demonstrated by the synthesis of several α-Me ketones up to 100 g amount The results came from multiple reactions, including the reaction of 1-Methyl-4-piperidone(cas: 1445-73-4Reference of 1-Methyl-4-piperidone)

1-Methyl-4-piperidone(cas: 1445-73-4) is a member of piperidine. Piperidine-containing compounds are also frequently employed in synthesis as ligands or auxiliaries. Accordingly, many efforts have been devoted to the development of novel methods for the synthesis of these compounds over the years.Reference of 1-Methyl-4-piperidone

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

HPLC of Formula: 1445-73-4In 2020 ,《Propargylated monocarbonyl curcumin analogues: synthesis, bioevaluation and molecular docking study》 appeared in Medicinal Chemistry Research. The author of the article were Nagargoje, Amol A.; Akolkar, Satish V.; Subhedar, Dnyaneshwar D.; Shaikh, Mubarak H.; Sangshetti, Jaiprakash N.; Khedkar, Vijay M.; Shingate, Bapurao B.. The article conveys some information:

Abstract: In the current exptl. study, we have synthesized new monocarbonyl curcumin analogs bearing propargyl ether moiety in their structure and evaluated for in vitro antifungal and radical scavenging activity. The antifungal activity was carried out against five human pathogenic fungal strains such as Candida albicans, Fusarium oxysporum, Aspergillus flavus, Aspergillus niger and Cryptococcus neoformans. Most of the curcumin analogs displayed excellent to moderate fungicidal activity when compared with standard drug Miconazole. Also, synthesized analogs exhibited potential radical scavenging activity as compared with standard antioxidant Butylated hydroxyl toluene (BHT). Based on biol. data, structure-activity relationship (SAR) were also discussed. Furthermore, in silico computational study was carried out to know binding interactions of synthesized analogs in the active sites of enzyme sterol 14α-demethylase (CYP51). [graphic not available: see fulltext] In addition to this study using 1-Methyl-4-piperidone, there are many other studies that have used 1-Methyl-4-piperidone(cas: 1445-73-4HPLC of Formula: 1445-73-4) was used in this study.

1-Methyl-4-piperidone(cas: 1445-73-4) is a member of piperidine. Piperidine-containing compounds are also frequently employed in synthesis as ligands or auxiliaries. Accordingly, many efforts have been devoted to the development of novel methods for the synthesis of these compounds over the years.HPLC of Formula: 1445-73-4

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Electric Literature of C6H11NOIn 2021 ,《In Situ-Doped Superacid in the Covalent Triazine Framework Membrane for Anhydrous Proton Conduction in a Wide Temperature Range from Subzero to Elevated Temperature》 was published in ACS Applied Materials & Interfaces. The article was written by Huang, Wenbo; Li, Bin; Wu, Yue; Zhang, Ying; Zhang, Wenxiang; Chen, Shuhui; Fu, Yu; Yan, Tong; Ma, Heping. The article contains the following contents:

Synthesis of solid-state proton-conducting membranes with low activation energy and high proton conductivity under anhydrous conditions is a great challenge. Here, we show a simple and convenient way to prepare covalent triazine framework membranes (CTF-Mx) with acid in situ doping for anhydrous proton conduction in a wide temperature range from subzero to elevated temperature (160 °C). The low proton dissociation energy and continuous hydrogen bond network in CTF-Mx make the membrane achieve high proton conductivity from 1.21×10-3 S cm-1 (-40 °C) to 2.08×10-2 S cm-1 (160 °C) under anhydrous conditions. Mol. dynamics and proton relaxation time analyses reveal proton hopping at low activation energies with greatly enhanced mobility in the CTF membranes. After reading the article, we found that the author used 1-Methyl-4-piperidone(cas: 1445-73-4Electric Literature of C6H11NO)

1-Methyl-4-piperidone(cas: 1445-73-4) is a member of piperidine. Piperidine-containing compounds are also frequently employed in synthesis as ligands or auxiliaries. Accordingly, many efforts have been devoted to the development of novel methods for the synthesis of these compounds over the years.Electric Literature of C6H11NO

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

In 2022,Lu, Shaoyong; Fu, Zhong; Li, Fu; Weng, Kangkang; Zhou, Likuan; Zhang, Lipeng; Yang, Yuchen; Qiu, Hengwei; Liu, Dan; Qing, Wenyue; Ding, He; Sheng, Xing; Chen, Menglu; Tang, Xin; Duan, Lian; Liu, Wenyong; Wu, Longjia; Yang, Yixing; Zhang, Hao; Li, Jinghong published an article in Angewandte Chemie, International Edition. The title of the article was 《Beyond a Linker: The Role of Photochemistry of Crosslinkers in the Direct Optical Patterning of Colloidal Nanocrystals》.Electric Literature of C6H11NO The author mentioned the following in the article:

Surface chem. mediated direct optical patterning represents an emerging strategy for incorporating colloidal nanocrystals (NCs) in integrated optoelectronic platforms including displays and image sensors. However, the role of photochem. of crosslinkers and other photoactive species in patterning remains elusive. Here we show the design of nitrene- and carbene-based photocrosslinkers can strongly affect the patterning capabilities and photophys. properties of NCs, especially quantum dots (QDs). Their role beyond phys. linkers stems from structure-dictated electronic configuration, energy alignment and associated reaction kinetics and thermodn. Patterned QD layers with designed carbene-based crosslinkers fully preserve their photoluminescent and electroluminescent properties. Patterned light emitting diodes (QLEDs) show a maximum external quantum efficiency of ∼12 % and lifetime over 4800 h, among the highest for reported patterned QLEDs. These results would guide the rational design of photoactive species in NC patterning and create new possibilities in the monolithic integration of NCs in high-performance device platforms. The experimental part of the paper was very detailed, including the reaction process of 1-Methyl-4-piperidone(cas: 1445-73-4Electric Literature of C6H11NO)

1-Methyl-4-piperidone(cas: 1445-73-4) is a member of piperidine. Piperidine is ubiquitous structural motif widely occurred in diverse synthetically and naturally occurring bioactive molecules. Piperidines are an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.Electric Literature of C6H11NO

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

In 2019,ACS Applied Materials & Interfaces included an article by Yan, Xiaoming; Zhang, Huaqing; Hu, Zhongyue; Li, Lv; Hu, Lei; Li, Zhi’ang; Gao, Li; Dai, Yan; Jian, Xigao; He, Gaohong. Application In Synthesis of 1-Methyl-4-piperidone. The article was titled 《Amphoteric-Side-Chain-Functionalized “”Ether-Free”” Poly(arylene piperidinium) Membrane for Advanced Redox Flow Battery》. The information in the text is summarized as follows:

To solve the stability issue of cost-effective non-fluorinated membranes, a ether-free poly(arylene piperidinium) (PBPip) based membrane is 1st applied in redox flow batteries (RFBs). For improved efficiencies of RFB, amphoteric side chains are introduced onto the PBPip. Without ether bond in the polymer backbone, the membrane shows a good stability in the strong oxidation environment. The FTIR spectra exhibit no obvious changes for 30 days of oxidation test. Different from traditional blended amphoteric membranes, the amphoteric side chain allows that cation and anion exchange capacities both increase with grafting degree, which leads to a very high total IEC (4.19 mmol/g). Outstanding ion conduction ability (area resistance: 0.22 Ω cm2) comparable to Nafion 212 (0.24 Ω cm2) is consequently achieved. Ionic crosslinking structure between cationic and anionic groups results in low swelling rate (13.9%). Combining with repelling effect of pos. charged piperidinium, a low VO2+ permeability (1.31×10-8 cm2/s) is accomplished. From these good properties, the membrane exhibits excellent vanadium battery performances, especially at high current densities. The WE and EE both exceeds 80% even at 200 mA/cm2. The battery performances have no obvious reductions after 500 cycles. This work provides a new orientation to design the membrane for RFB. In the experiment, the researchers used many compounds, for example, 1-Methyl-4-piperidone(cas: 1445-73-4Application In Synthesis of 1-Methyl-4-piperidone)

1-Methyl-4-piperidone(cas: 1445-73-4) is a member of piperidine. Piperidine is a key saturated heterocyclic scaffold found in several of the top-selling small molecule pharmaceuticals and natural alkaloids, with a diverse range of biological activities. Hence, continuous efforts have been made to develop convenient methods to prepare piperidine derivatives.Application In Synthesis of 1-Methyl-4-piperidone

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

In 2022,Nagarale, Rajaram. K.; Bavdane, Priyanka P.; Sreenath, Sooraj; Pawar, Chetan M.; Dave, Vidhiben; Satpati, A. K. published an article in Journal of Polymer Research. The title of the article was 《Polyaniline derivatized anion exchange membrane for acid recovery》.Related Products of 1445-73-4 The author mentioned the following in the article:

Herein we are demonstrating the utility of an aniline derivatized anion exchange membrane for acid recovery by diffusion dialysis. The membrane was synthesized by oxidative polymerization of N-Methyl-4-piperidone derivative and confirmed by detailed spectroscopic characterisations. Free-standing membranes M1 and M2 was obtained by addition of different amount of PVA. For the comparison purpose, PVA blend with neat polyaniline was synthesized. Excellent physicochem. properties coupled with outstanding chem. stability in bentonite mine effluent with total acid concentration of ∼ 8 M, drawn interest to use in acid recovery by diffusion dialysis. In a simulated solution containing 6% iron and 3.5 M HCl, calculated proton dialysis coefficient (UH+) was 31 x 10-3 m h-1 and iron dialysis coefficient (UFe2+) was 3 x 10-4 m h-1 for the best membrane M2. It corresponded to separation factor (S) of 103 units, which was comparable with literature known best membranes like Neosepta. For effluent solution obtained from a local bentonite mine, membrane M2 showed UH+ value of 37 x 10-3 m h-1 and UFe2+ value of 6 x 10-4 m h-1 suggesting its best utility in acid recovery. In the experiment, the researchers used many compounds, for example, 1-Methyl-4-piperidone(cas: 1445-73-4Related Products of 1445-73-4)

1-Methyl-4-piperidone(cas: 1445-73-4) is a member of piperidine. Piperidine is a key saturated heterocyclic scaffold found in several of the top-selling small molecule pharmaceuticals and natural alkaloids, with a diverse range of biological activities. Hence, continuous efforts have been made to develop convenient methods to prepare piperidine derivatives.Related Products of 1445-73-4

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

《A novel and simple strategy for the synthesis of γ-carboline》 was published in Eurasian Chemical Communications in 2020. These research results belong to Gaikwad, Sunil V.; Gaikwad, Milind V.; Lokhande, Pradeep D.. Reference of 1-Methyl-4-piperidone The article mentions the following:

This study introduces a novel and efficient approach for the oxidative aromatization of tetrahydro-γ-carbolines I (R = H, Me, Bn; R1 = H, Cl; R2 = H, Me, Cl, F) using CuCl2.2H2O and I2, H2O2 in DMSO. This method was applied for all kinds of C-3 substituted tetrahydro-γ-carbolines (THγC) I units to access the corresponding aromatic γ-carbolines II. With a 0.25 mol% CuCl2.2H2O as a catalyst, THγC I could be efficiently oxidized to γ-carbolines II at 100°C with excellent yield. This protocol was also generalized for the aromatization of tetrahydro-β-carboline-3-carboxylic acids III (Ar = 3-bromophenyl, 4-methylphenyl, 4-(propan-2-yl)phenyl, 3,4,5-trimethoxyphenyl) to corresponding β-carboline-3-carboxylic acids IV. The entire synthesized new compounds II and IV were characterized by using 1HNMR, 13CNMR and Mass spectroscopy technique. To the best of knowledge, this is the first synthesis of γ-carbolines II via an oxidative aromatization of THγC I. In the part of experimental materials, we found many familiar compounds, such as 1-Methyl-4-piperidone(cas: 1445-73-4Reference of 1-Methyl-4-piperidone)

1-Methyl-4-piperidone(cas: 1445-73-4) is a member of piperidine. Piperidine-containing compounds are also frequently employed in synthesis as ligands or auxiliaries. Accordingly, many efforts have been devoted to the development of novel methods for the synthesis of these compounds over the years.Reference of 1-Methyl-4-piperidone

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem