Category: 1445-73-4

The author of 《Robust poly(aryl piperidinium)/N-spirocyclic poly(2,6-dimethyl-1,4-phenyl) for hydroxide-exchange membranes》 were Chen, Nanjun; Lu, Chuanrui; Li, Yunxi; Long, Chuan; Zhu, Hong. And the article was published in Journal of Membrane Science in 2019. Recommanded Product: 1-Methyl-4-piperidone The author mentioned the following in the article:

Herein, for realizing the high efficiency and long lifetime of hydroxide exchange membranes (HEMs) for alk. membrane fuel cell (AMFC) applications, a series of robust poly(biphenyl piperidinium) (PBP)/6-azaspiro[5.5] undecane (ASU)-functionalized polyphenyl ether (ASU-PPO) membranes were prepared by a crosslinked strategy. Crosslinked PBP-ASU-PPO membrane combines the advantage of PBP and ASU-PPO membranes as well as addresses the problem of high water uptake of PBP and the insufficient film-forming property of ASU-PPO. As expected, these crosslinked PBP-ASU-PPO membranes exhibit commendably comprehensive performances, such as good ion conductivity, durability, and mech. properties. The crosslinked PBP-ASU-PPO membrane reaches a maximum OH- conductivity of 128 mS/cm at 80 °C, accompanying with a 15.7% membrane swelling. Besides, only 13.6% degradation in Cl- conductivity was observed in PBP-ASU-PPO after alk. treatment in 1 M NaOH at 80 °C for 2000 h. Besides, the selected PBP-ASU-PPO membrane achieves a maximum power d. of 324 mW/cm2 at c.d. of 750 mA/cm2. The results came from multiple reactions, including the reaction of 1-Methyl-4-piperidone(cas: 1445-73-4Recommanded Product: 1-Methyl-4-piperidone)

1-Methyl-4-piperidone(cas: 1445-73-4) is a member of piperidine. Piperidine-containing compounds are also frequently employed in synthesis as ligands or auxiliaries. Accordingly, many efforts have been devoted to the development of novel methods for the synthesis of these compounds over the years.Recommanded Product: 1-Methyl-4-piperidone

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Name: 1-Methyl-4-piperidoneIn 2020 ,《Chemically stable poly(meta-terphenyl piperidinium) with highly conductive side chain for alkaline fuel cell membranes》 appeared in Journal of Membrane Science. The author of the article were Lu, Chuanrui; Long, Chuan; Li, Yunxi; Li, Ziming; Zhu, Hong. The article conveys some information:

Poly(arylene piperidine)s (PAPs) backbones, which do not contain unstable ether bonds, was synthesized by one-pot, metal-free superacid-catalyzed polymerization for anion exchange membranes (AEMs) preparation Meta-terphenyl as a monomer of polymer to regulate the morphol. and properties of AEM was also used due to its spatially torsional configuration instead of the recently reported linear structure of meta-terphenyl. Long flexible hydrophilic chains were grafted onto poly(meta terphenyl piperidinium) (m-PTP) backbone to form four cationic functionalized side chains, promoting efficient transfer of OH- and optimizing the hydrophilic/hydrophobic microphase separation structure. The resulting AEM shows a high ion conductivity of 164 mS/cm (m-PTP-TFPE-21) at 80°C. Furthermore, stable piperidine cation and long alkyl spacer chain contributed to the excellent alkali stability of m-PTP-TFPE-TQA membrane which shows only 11.67% and 12.73% degradation in ion conductivity and IEC, resp., after soaking in 2 M NaOH at 80°C for 1500 h. The peak power d. of the H2/O2 single cell using m-PTP-TFPE-14 is 269 mW/cm2 at a c.d. of 540 mA/cm2 at 80°C. The results came from multiple reactions, including the reaction of 1-Methyl-4-piperidone(cas: 1445-73-4Name: 1-Methyl-4-piperidone)

1-Methyl-4-piperidone(cas: 1445-73-4) is a member of piperidine. Piperidine is ubiquitous structural motif widely occurred in diverse synthetically and naturally occurring bioactive molecules. Piperidines are an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.Name: 1-Methyl-4-piperidone

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

In 2022,Yang, Lincan; Wang, Zhiqian; Wang, Fanghui; Wang, Zhongming; Zhu, Hong published an article in Journal of Membrane Science. The title of the article was 《Poly(aryl piperidinium) anion exchange membranes with cationic extender sidechain for fuel cells》.Electric Literature of C6H11NO The author mentioned the following in the article:

Anion-exchange membrane fuel cells (AEMFCs) is a promising solution to decrease the cost of fuel cell, because it is adaptable to non-noble-metals catalysts and low-cost stack components. However, anion exchange membranes (AEMs), a crucial component of AEMFCs devices, with desired properties (high ions conductivity, excellent chem. stability, robust mech. strength, etc.) are currently unavailable. In this paper, poly(biphenyl N-methylpiperidine) (PBP) was synthesized as the backbones of AEMs, which could provide good chem. stability and robust mech. strength. Quaternary ammonium cations containing various types of substituent sidechains, including hydrophobic alkyl chain, hydrophilic PEG chain and multi-PEG chains, were introduced onto the PBP backbones, and resulting AEMs were named PBP-alkyl, PBP-PEG and PBP-TPEG, resp. The relationship between AEMs structure and performance were studied, and mol. dynamics (MD) simulations were carried out to microcosmically reveal the mechanism of structure-activity relationship. All the PBP-based AEMs have acceptable alk. stability and performance loss is less than 10% under 2 M NaOH at 80 °C for about 500 h. PBP-PEG has the highest ions conductivity of 97.3 mS cm-1 and lowest water uptake (WU), while PBP-TPEG has the lowest ions conductivity of 56.1 mS cm-1 and highest WU. For single cell evaluations at 80 °C under H2/O2 condition, AEMFC containing PBP-PEG membrane bursts out a highest peak power d. of 373 mW cm2, while PBP-alkyl and PBP-TPEG only achieve 133 and 93 mW cm-2, resp. MD results show the water channel of PBP-PEG is denser and more continuous than other structures, and the proportion of completely hydrated transport is higher than other structures, which contributes to the increase of overall performance. On the other hand, DFT results show the low basicity and strong hydrophily of cation containing multi-PEG substituents leads to the poor performance of PBP-TPEG. Therefore, for the design of AEMs mol. structures with outstanding performances, hydrophilic PEG spacer chain is more effective than hydrophobic alkyl spacer chain, and PEG is more effective as a spacer chain than as an extender chain. The experimental part of the paper was very detailed, including the reaction process of 1-Methyl-4-piperidone(cas: 1445-73-4Electric Literature of C6H11NO)

1-Methyl-4-piperidone(cas: 1445-73-4) is a member of piperidine. Piperidine is ubiquitous structural motif widely occurred in diverse synthetically and naturally occurring bioactive molecules. Piperidines are an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.Electric Literature of C6H11NO

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

In 2022,Kim, Hae Min; Hu, Chuan; Wang, Ho Hyun; Park, Jong Hyeong; Chen, Nanjun; Lee, Young Moo published an article in Journal of Membrane Science. The title of the article was 《Impact of side-chains in poly(dibenzyl-co-terphenyl piperidinium) copolymers for anion exchange membrane fuel cells》.Application of 1445-73-4 The author mentioned the following in the article:

Anion exchange membrane fuel cells (AEMFCs) have experienced rapid advancement in the past few years due to the discovery of high-performance AEMs and ionomers. Here, we report a series of side-chain-type poly(dibenzbeyl-co-terphenyl piperidinium) (s-PDTP) copolymers as ionomers and membranes for AEMFC applications. The features of aryl ether-free PDTP polymer backbone and pendent ammonium groups endow both high alk. stability and excellent micromorphol. to s-PDTP copolymers. These ion-exchange-capacity (IEC)-controlled s-PDTP membranes possess high OH- conductivity >120 mS cm-1 at 80 °C, reasonable mol. weight (Mw = 150-290 kDa), and excellent ex-situ durability in 1 M NaOH at 80 °C for 1000 h (∼90% conductivity remaining). For ionomer research, s-PDTP ionomers with moderate IEC (∼3.0 mmol g-1) and rational water uptake (∼200%) exhibit optimal AEMFC performance based on a PDTP membrane compared to high-IEC or low-IEC s-PDTP ionomers (>3.4 mmol g-1 or <2.4 mmol g-1). Based on Pt/C, s-PDTP-based AEMFCs reach a peak power d. (PPD) of 1.47 W cm-2 in H2-O2 and 1.04 W cm-2 in H2-air (CO2-free) at 80 °C. The results came from multiple reactions, including the reaction of 1-Methyl-4-piperidone(cas: 1445-73-4Application of 1445-73-4)

1-Methyl-4-piperidone(cas: 1445-73-4) is a member of piperidine. Piperidine is a key saturated heterocyclic scaffold found in several of the top-selling small molecule pharmaceuticals and natural alkaloids, with a diverse range of biological activities. Hence, continuous efforts have been made to develop convenient methods to prepare piperidine derivatives.Application of 1445-73-4

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

In 2022,Gou, Wei Wei; Gao, Wei Ting; Gao, Xue Lang; Zhang, Qiu Gen; Zhu, Ai Mei; Liu, Qing Lin published an article in Journal of Membrane Science. The title of the article was 《Highly conductive fluorinated poly(biphenyl piperidinium) anion exchange membranes with robust durability》.COA of Formula: C6H11NO The author mentioned the following in the article:

To prepare anion exchange membranes (AEMs) that possess an excellent alk. resistance, a competitive conductivity and a low swelling ratio (SR), a reasonable mol. structure design is particularly important. Herein, we synthesized ether-free fluoropolymers via a superacid catalyzed polyhydroxyalkylation reaction in one pot, and grafted long flexible multipiperidine cation side chains to different positions of the backbone through Menshutkin reaction. We investigated the effect of hydrophilic-hydrophobic polarity difference on the microphase separation When the ionic liquid is grafted closer to the fluorine-contained group, AEMs exhibit a more obvious microphase separated structure and larger ion clusters as confirmed by morphol. observation. Mol. dynamics simulations also confirmed that the construction of ion channels in PBPip-QAPBF-30% is more efficient than in QAPBPip-PBF-30%. The resulting PBPip-QAPBF-30% AEM exhibits the highest OH- conductivity of 156.4 mS cm-1 with a low SR of 12.9% at 80°C. The QAPBPip-PBF-30% and PBPip-QAPBF-30% AEMs both show an excellent alk. stability with the OH- conductivity retention of 93.2% and 95.0% correspondingly after being treated in a 2 M NaOH solution at 80°C for 1080 h. Moreover, the peak power d. of a single cell equipped with PBPip-QAPBF-30% reaches 324.5 mW cm-2 at a c.d. of 550 mA cm-2. In addition to this study using 1-Methyl-4-piperidone, there are many other studies that have used 1-Methyl-4-piperidone(cas: 1445-73-4COA of Formula: C6H11NO) was used in this study.

1-Methyl-4-piperidone(cas: 1445-73-4) is a member of piperidine. Piperidine is ubiquitous structural motif widely occurred in diverse synthetically and naturally occurring bioactive molecules. Piperidines are an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.COA of Formula: C6H11NO

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Ma, Lingling; Hussain, Manzoor; Li, Lv; Qaisrani, Naeem Akhtar; Bai, Lei; Jia, Yabin; Yan, Xiaoming; Zhang, Fengxiang; He, Gaohong published an article in 2021. The article was titled 《Octopus-like side chain grafted poly(arylene piperidinium) membranes for fuel cell application》, and you may find the article in Journal of Membrane Science.COA of Formula: C6H11NO The information in the text is summarized as follows:

Octopus-like side chains are introduced in poly(arylene piperidinium)-based alk. anion exchange membranes (AEMs) to enhance the conductivity and stability. This type of side chain consists of a bulky rigid β-cyclodextrin (β-CD) as the “”octopus head””, and long flexible piperidinium ionic liquids as the “”arms””. The β-CD unit can enlarge internal free volume of the AEM to reduce ion transport resistance; the “”arms”” can interact with adjacent hydrophilic ionic groups and water, constructing continuous ion transport channels. The prepared poly(biphenyl piperidinium) AEM with “”octopus”” side chains at an ion exchange capacity (IEC) of 1.29 mmol g-1 exhibits higher hydroxide conductivity (121.5 mS cm-1 at 80°C) than that without the “”octopus”” structure (57.4 mS cm-1) although the latter has a larger IEC (1.55 mmol g-1). This “”octopus”” AEM retains 87.2% of its conductivity after being treated in a 1 M NaOH at 80°C for 480 h. The alk. H2/O2 fuel cell constructed with this “”octopus”” AEM produces a peak power d. of 469 mW cm-2; the cell voltage can be maintained by 85% during 16 h operation. This work illustrates the advantage of “”octopus”” side chain for enhancement of AEM performance. In addition to this study using 1-Methyl-4-piperidone, there are many other studies that have used 1-Methyl-4-piperidone(cas: 1445-73-4COA of Formula: C6H11NO) was used in this study.

1-Methyl-4-piperidone(cas: 1445-73-4) is a member of piperidine. Piperidine is ubiquitous structural motif widely occurred in diverse synthetically and naturally occurring bioactive molecules. Piperidines are an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.COA of Formula: C6H11NO

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Pediconi, Natalia; Ghirga, Francesca; Del Plato, Cristina; Peruzzi, Giovanna; Athanassopoulos, Constantinos M.; Mori, Mattia; Crestoni, Maria Elisa; Corinti, Davide; Ugozzoli, Franco; Massera, Chiara; Arcovito, Alessandro; Botta, Bruno; Boffi, Alberto; Quaglio, Deborah; Baiocco, Paola published an article in 2021. The article was titled 《Design and Synthesis of Piperazine-Based Compounds Conjugated to Humanized Ferritin as Delivery System of siRNA in Cancer Cells》, and you may find the article in Bioconjugate Chemistry.HPLC of Formula: 1445-73-4 The information in the text is summarized as follows:

Gene expression regulation by small interfering RNA (siRNA) holds promise in treating a wide range of diseases through selective gene silencing. However, successful clin. application of nucleic acid-based therapy requires novel delivery options. Herein, to achieve efficient delivery of neg. charged siRNA duplexes, the internal cavity of “”humanized”” chimeric Archaeal ferritin (HumAfFt) was specifically decorated with novel cationic piperazine-based compounds (PAs). By coupling these rigid-rod-like amines with thiol-reactive reagents, chemoselective conjugation was efficiently afforded on topol. selected cysteine residues properly located inside HumAfFt. The capability of PAs-HumAfFt to host and deliver siRNA mols. through human transferrin receptor (TfR1), overexpressed in many cancer cells, was explored. These systems allowed siRNA delivery into HeLa, HepG2, and MCF-7 cancer cells with improved silencing effect on glyceraldehyde-3-phosphate dehydrogenase (GAPDH) gene expression with respect to traditional transfection methodologies and provided a promising TfR1-targeting system for multifunctional siRNA delivery to therapeutic applications. In the experiment, the researchers used 1-Methyl-4-piperidone(cas: 1445-73-4HPLC of Formula: 1445-73-4)

1-Methyl-4-piperidone(cas: 1445-73-4) is a member of piperidine. Piperidine is a key saturated heterocyclic scaffold found in several of the top-selling small molecule pharmaceuticals and natural alkaloids, with a diverse range of biological activities. Hence, continuous efforts have been made to develop convenient methods to prepare piperidine derivatives.HPLC of Formula: 1445-73-4

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Zhou, Xixing; Wu, Lexuan; Zhang, Guangxu; Li, Ruyu; Hu, Xu; Chang, Xuanwei; Shen, Yinghua; Liu, Lei; Li, Nanwen published their research in Journal of Membrane Science in 2021. The article was titled 《Rational design of comb-shaped poly(arylene indole piperidinium) to enhance hydroxide ion transport for H2/O2 fuel cell》.Category: piperidines The article contains the following contents:

To produce anion exchange membranes (AEMs) possessing high conductivity and chem. stability, we propose a ternary copolymerization strategy to prepare comb-shaped poly(arylene indole piperidinium) copolymers with different lengths of side chain by the design of alkyl-functionalized isatin comonomers in the acid-catalyzed Friedel-Crafts polycondensations of N-methyl-4-piperidone and p-terphenyl. These polymers have a characteristic feature of hydrophobic side chain sep. attached onto aryl-ether free backbones to induce microphase separated morphol. and stable piperidinium cation within the backbone to ensure the alk. stability. PITP-C10Q85 membrane with C10 side chain showed the highest hydroxide conductivity of 134.5 mS/cm at 80 °C due to the formed microphase separated morphol. Alk. stability testing in 1 M NaOH at 80 °C demonstrated that 80% of initial conductivity was retained for PITP-C10Q85 membrane after 1200 h of testing, owning to the chem. degradation of piperidinium cation in comb-shaped membranes via Hoffman elimination and nucleophilic substitution reaction. By assembling in alk. fuel cells, PITP-C10Q85 membrane delivered a peak power d. of 445 mW/cm2 at a c.d. of 870 mA/cm2 at 60 °C. Meanwhile, in-situ stability of PITP-C10Q85 membrane demonstrated a voltage decay rate of 3.67 mV/h over 75 h of operating at 300 mA/cm2, and post-cell anal. of the aged membrane revealed that predominant nucleophilic substitution reaction was found for the degradation of PITP-C10Q85 membrane, being different from the degradation mechanisms in the ex-situ stability tests. The above results manifested that regulating the alkyl side chains on the backbone directly is a promising strategy to achieve high performance AEMs with favorable morphol., high conductivity and alk. fuel cell performance. In the experiment, the researchers used many compounds, for example, 1-Methyl-4-piperidone(cas: 1445-73-4Category: piperidines)

1-Methyl-4-piperidone(cas: 1445-73-4) is a member of piperidine. Piperidine is a key saturated heterocyclic scaffold found in several of the top-selling small molecule pharmaceuticals and natural alkaloids, with a diverse range of biological activities. Hence, continuous efforts have been made to develop convenient methods to prepare piperidine derivatives.Category: piperidines

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Chen, Nanjun; Hu, Chuan; Wang, Ho Hyun; Park, Jong Hyeong; Kim, Hae Min; Lee, Young Moo published their research in Journal of Membrane Science in 2021. The article was titled 《Chemically & physically stable crosslinked poly(aryl-co-aryl piperidinium)s for anion exchange membrane fuel cells》.Reference of 1-Methyl-4-piperidone The article contains the following contents:

Poly(aryl-co-aryl piperidinium) (c-PAP) copolymers have recently demonstrated great successes in anion exchange membranes (AEMs) and ionomers for AEM fuel cells (AEMFCs). Here, we present a series of in-situ styrene-crosslinked c-PAP (x-PAP-PS) membranes to further enhance the mech. strength, dimensional stability, and water retention capacity of c-PAP AEMs. Specifically, x-PAP-PS AEMs simultaneously possess high ion conductivity (>150 mS cm-1), tensile strength (>80 MPa), and chem. and mech. durability (∼90% ion conductivity and mech. strength maintaining in 1 M NaOH at 80°C for 2160 h). Addnl., x-PAP-PS-based AEMFCs reached peak power densities (PPDs) of 2.23 W cm-2 in H2-O2 and 1.32 W cm-2 in H2-air at 80°C. Importantly, compared to pristine c-PAP AEMs, x-PAP-PS AEMs display higher water retention capacity at low relative humidity (RH), and the corresponding AEMFCs reach PPDs >1 W cm-2 with Pt/C at 30%/30% RH at 90°C. Moreover, the x-PAP-PS-based AEMFCs can be operated stably under a 0.4 A cm-2 c.d. at 60°C for ∼120 h. The results came from multiple reactions, including the reaction of 1-Methyl-4-piperidone(cas: 1445-73-4Reference of 1-Methyl-4-piperidone)

1-Methyl-4-piperidone(cas: 1445-73-4) is a member of piperidine. Piperidine is ubiquitous structural motif widely occurred in diverse synthetically and naturally occurring bioactive molecules. Piperidines are an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.Reference of 1-Methyl-4-piperidone

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Chen, Sheng; Peng, Hanqing; Hu, Meixue; Wang, Gongwei; Xiao, Li; Lu, Juntao; Zhuang, Lin published their research in ACS Applied Energy Materials in 2021. The article was titled 《Ultrathin Self-Cross-Linked Alkaline Polymer Electrolyte Membrane for APEFC Applications》.Reference of 1-Methyl-4-piperidone The article contains the following contents:

Ultrathin alk. polymer electrolyte (APE) membranes have become a hot research topic for high-performance alk. polymer electrolyte fuel cells (APEFCs). To our knowledge, freestanding ultrathin membranes with thicknesses of or below 10 μm have never been reported for successful applications in APEFCs. The obstacle comes from the poor mech. strength of the ultrathin membrane during the fuel cell assembly. Herein we report an ultrathin 10 μm membrane made of cross-linked quaternary ammonia poly(N-methylpiperidine-co-p-terphenyl), denoted cQAPPT. This ultrathin cQAPPT membrane is robust enough for fuel cell assembly and demonstrates a high H2/O2 peak power d. of 1.85 W/cm2 at 80 °C. In the part of experimental materials, we found many familiar compounds, such as 1-Methyl-4-piperidone(cas: 1445-73-4Reference of 1-Methyl-4-piperidone)

1-Methyl-4-piperidone(cas: 1445-73-4) is a member of piperidine. Piperidine is a key saturated heterocyclic scaffold found in several of the top-selling small molecule pharmaceuticals and natural alkaloids, with a diverse range of biological activities. Hence, continuous efforts have been made to develop convenient methods to prepare piperidine derivatives.Reference of 1-Methyl-4-piperidone

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem