Reynoso, Dianne B. et al. published their research in European Journal of Biomedical and Pharmaceutical Sciences in 2021 | CAS: 129-74-8

1-(4-(tert-Butyl)benzyl)-4-((4-chlorophenyl)(phenyl)methyl)piperazine dihydrochloride (cas: 129-74-8) belongs to piperazine derivatives. Simple N-substituted piperazines have been found in many drug molecules. Piperazine and its salts did not induce point mutations in a bacterial test. A series of mutagenicity studies in cells, both in vitro and in vivo, has been completed and showed no evidence of mutagenic effect.Application of 129-74-8

Perception of consumers towards the use of auxiliary labels for over-the-counter and prescription drugs in promoting medication adherence in Luzon was written by Reynoso, Dianne B.;Ayala, Sofia Clarisa P.;Macalincag, Jersey Ann Marie V.;Navarro, Mart Jayzon R.;Paloma, Bon Lorn D.;Racho, Elaine Nicole P.;Andal, Mylene S.;Ecalne, Jan Karlo T.. And the article was included in European Journal of Biomedical and Pharmaceutical Sciences in 2021.Application of 129-74-8 This article mentions the following:

The quant. study aimed to determine Filipino medication consumers′ perception on the use of auxiliary labels on over-the-counter and prescription drugs and assess effectiveness in the three aspects of patient confusion (cognitive, affective, and behavioral). Mode, frequency, and regression anal. were utilized in the data anal. Participants were predominantly women (52.79%), aged 18-25 (68%), and graduates of bachelor′s degrees (42.67%). The consumers′ perception towards the use of auxiliary labels on over-the-counter and prescription drugs is highly accepted in terms of its effectiveness and the three aspects of patient confusion. Consumers perceive them as easy to understand (n = 122, 81.33%), ensure safety (n = 125, 83.33%), proper administration of medication (n = 124, 82.67%), and should be implemented in the Philippines (n = 137, 91.33%). Pharmacists (p = 0.0273) and internet (p = 0.0296) as sources of medication information and being male (p = 0.0182) had a significant relationship with affective and behavioral aspects, resp. Medication consumers prefer the use of auxiliary labels as it aids in medication adherence. Researchers′ recommendations are in-depth qual. research with different settings, backgrounds, and populations for comparable results, and a study on pharmacists′ perception and male gender in the use of auxiliary labels. In the experiment, the researchers used many compounds, for example, 1-(4-(tert-Butyl)benzyl)-4-((4-chlorophenyl)(phenyl)methyl)piperazine dihydrochloride (cas: 129-74-8Application of 129-74-8).

1-(4-(tert-Butyl)benzyl)-4-((4-chlorophenyl)(phenyl)methyl)piperazine dihydrochloride (cas: 129-74-8) belongs to piperazine derivatives. Simple N-substituted piperazines have been found in many drug molecules. Piperazine and its salts did not induce point mutations in a bacterial test. A series of mutagenicity studies in cells, both in vitro and in vivo, has been completed and showed no evidence of mutagenic effect.Application of 129-74-8

Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics

 

Kishore, M. et al. published their research in Analytical Chemistry: An Indian Journal in 2010 | CAS: 129-74-8

1-(4-(tert-Butyl)benzyl)-4-((4-chlorophenyl)(phenyl)methyl)piperazine dihydrochloride (cas: 129-74-8) belongs to piperazine derivatives. Piperazine belongs to the family of medicines called anthelmintics. Intermediate for a wide range of pharmaceuticals, polymers, dyes, corrosion inhibitors, rubber accelerators and surfactants.Formula: C28H35Cl3N2

Spectrophotometric determination of buclizine and pyrilamine in pharmaceutical formulations by Tpooo was written by Kishore, M.;Hanumantharao, Y.. And the article was included in Analytical Chemistry: An Indian Journal in 2010.Formula: C28H35Cl3N2 This article mentions the following:

A simple, sensitive, selective and accurate spectrophotometric method Tpooo for the determination of buclizine (BUCZ) and pyrilamine (PYRA) in bulk drug and pharmaceutical formulations (tablets) was described. This method is based on the extraction of drugs into organic layer of the dye Tpooo in presence of 0.1 N hydrochloric acid and the absorbances were measured at 480 nm. The results of anal. for this method have been validated statistically and by recovery studies. In the experiment, the researchers used many compounds, for example, 1-(4-(tert-Butyl)benzyl)-4-((4-chlorophenyl)(phenyl)methyl)piperazine dihydrochloride (cas: 129-74-8Formula: C28H35Cl3N2).

1-(4-(tert-Butyl)benzyl)-4-((4-chlorophenyl)(phenyl)methyl)piperazine dihydrochloride (cas: 129-74-8) belongs to piperazine derivatives. Piperazine belongs to the family of medicines called anthelmintics. Intermediate for a wide range of pharmaceuticals, polymers, dyes, corrosion inhibitors, rubber accelerators and surfactants.Formula: C28H35Cl3N2

Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics