《Optical resolution of amino acid derivatives by high-performance liquid chromatography on tris(phenylcarbamate)s of cellulose and amylose》 was written by Okamoto, Yoshio; Kaida, Yuriko; Aburatani, Ryo; Hatada, Koichi. Formula: C16H21NO4 And the article was included in Journal of Chromatography on August 30 ,1989. The article conveys some information:
The optical resolution of 10 N-protected alanine esters was examined by HPLC using 6 cellulose and 5 amylose tris(phenylcarbamate) derivatives as chiral stationary phases. Tris(3,5-dimethylphenylcarbamate)s of both cellulose and amylose showed high resolving power for these racemates. The resolution of 23 N-benzyloxycarbonyl α-amino acid ester was also tested on tris(3,5-dimethylphenylcarbamate)s of cellulose and amylose. All but 2 amino acid derivatives were completely resolved at least by one of the columns. On cellulose tris(3,5-dimethylphenylcarbamate), all L-amino acids (except threonine) eluted first. In the experiment, the researchers used 1-Benzyl 2-ethyl piperidine-1,2-dicarboxylate(cas: 126401-22-7Formula: C16H21NO4)
1-Benzyl 2-ethyl piperidine-1,2-dicarboxylate(cas: 126401-22-7) belongs to piperidines. Piperidine derivatives are also used in solid-phase peptide synthesis (SPPS) and many degradation reactions. Formula: C16H21NO4
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem