Category: 117896-69-2

Application of 117896-69-2, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.117896-69-2, Name is 1-Phenylpiperidin-4-ol, molecular formula is C11H15NO. In a Article，once mentioned of 117896-69-2

The cascade aza-Cope/aza-Prins cyclization of homoallylamines to give substituted piperidines has been explored. The use of glyoxalic acid as the carbonyl component afforded bicyclic structures as a result of the internal carboxylate anion trapping the intermediate cation. The unimolecular bis-, tris-, and tetrakis(homoallylamine)s efficiently delivered the appended bis-, tris- and tetrakis(piperidine-4-ol)s (tripod and crucifix shape, respectively) as new entities. The latter compound served as an excellent ligand in the Suzuki-Miyaura cross-coupling reaction to synthesize incrustoporin. The cascade aza-Cope/aza-Prins cyclization of homoallylamines to give substituted piperidines is described. A unimolecular tetrapiperidine derivative, which resulted from this strategy, was employed as a ligand in the Suzuki-Miyaura cross-coupling reaction of an alpha-iodobutenolide with an arylboronic acid in an efficient synthesis of incrustoporin and its analogues.

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Reference：
Piperidine – Wikipedia,
Piperidine | C5H10750N – PubChem

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, Computed Properties of C11H15NO, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 117896-69-2, Name is 1-Phenylpiperidin-4-ol, molecular formula is C11H15NO. In a Patent, authors is ，once mentioned of 117896-69-2

The synthesis method comprises the following steps: N – dissolving the aniline in diethyl ether, adding the catalyst 5 – adding the catalyst 3 – under stirring, carrying out reflux reaction under stirring conditions, filtering N – and 3 distilling under reduced pressure N . The synthesis method is simple in preparation process, short in production process, high in raw material conversion rate, low in production cost and high in economic benefit. (by machine translation)

Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. I hope my blog about is helpful to your research. Computed Properties of C11H15NO

Reference：
Piperidine – Wikipedia,
Piperidine | C5H10746N – PubChem

Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 117896-69-2, molcular formula is C11H15NO, introducing its new discovery. Recommanded Product: 117896-69-2

The present invention relates to compounds that inhibit a5b1 function, processes for their preparation, pharmaceutical compositions containing them as the active ingredient, to their use as medicaments and to their use in the manufacture of medicaments for use in the treatment in warm blooded animals such as humans of diseases that have a significant angiogenesis or vascular component such as for treatment of solid tumours. The present invention also relates to compounds that inhibit a5b1, and also that exhibit appropriate selectivity profile(s) against other integrins.

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Reference：
Piperidine – Wikipedia,
Piperidine | C5H10747N – PubChem

Electric Literature of 117896-69-2, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.117896-69-2, Name is 1-Phenylpiperidin-4-ol, molecular formula is C11H15NO. In a Patent，once mentioned of 117896-69-2

This invention provides Degronimers that have E3 Ubiquitin Ligase targeting moieties (Degrons) that can be linked to a targeting ligand for a protein that has been selected for in vivo degradation, and methods of use and compositions thereof as well as methods for their preparation. The invention also provides Degrons that can be used to treat disorders mediated by cereblon or an Ikaros family protein, and methods of use and compositions thereof as well as methods for their preparation.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 117896-69-2

Reference：
Piperidine – Wikipedia,
Piperidine | C5H10745N – PubChem

Related Products of 117896-69-2, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.117896-69-2, Name is 1-Phenylpiperidin-4-ol, molecular formula is C11H15NO. In a Article，once mentioned of 117896-69-2

The comparative rates of acid-catalysed removal often 1-aryl-4-methoxypiperidin-4-yl 8 (R = Me) [including the previously reported Ctmp 5 and Fpmp 6] protecting groups for the 2?-hydroxy functions in oligoribonucleotide synthesis are discussed. These studies have led to the development of the 1-(4-chlorophenyl)-4-ethoxypiperidin-4-yl (Cpep) protecting group 8 (R = Et, R1 = R2 = H, R3 = Cl) which is both more stable than the Ctmp and Fpmp groups at pH 0.5 and more labile at pH 3.75. The influence of the ribonucleoside aglycone on the stability of the 2?-O-Fpmp and 2?-O-Ctmp protecting groups both at low and high pH is examined. The Royal Society of Chemistry 2000.

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Reference：
Piperidine – Wikipedia,
Piperidine | C5H10749N – PubChem

117896-69-2, 1-Phenylpiperidin-4-ol is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Example 40 Methyl AL(fe/^-butoxyearbonyl)-Methyl N-(tert-butoxycarbonyl)-L-tyrosinate (1.05 g), triphenylphosphine (1.40 g) and 4-hydroxy-l-phenylpiperidine (0.95 g) were dissolved in DCM and cooled to O0C. DTAD (1.25 g) was added slowly maintaining T< 5 0C. The reaction mixture was stirred overnight at room temperature then concentrated in vacuo and the residue purified by chromatography using iso-hexane - 10% ethyl acetate to 50% ethyl acetate as eluent to give the title compound as a yellow solid (1.91 g, 79%).1H NMR Spectrum (DMSO-d6) 1.33 (9H, s), 1.70 (2H, m), 2.04 (IH, m), 2.84 (2H, m), 3.04 (2H, t), 3.50 (2H5 m), 3.61 (3H, s), 4.12 (IH, m), 4.51 (IH, t), 6.76 (IH, t), 6.93 (4H, dd), 7.18 (5H, m).Mass Spectrum [M+H]+ = 455 117896-69-2, As the paragraph descriping shows that 117896-69-2 is playing an increasingly important role.

Reference£º
Patent; ASTRAZENECA AB; ASTRAZENECA UK LIMITED; WO2007/91046; (2007); A1;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem