Category: 1171080-45-7

Reference of 1171080-45-7, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.1171080-45-7, Name is (2S,5R)-Benzyl 5-((benzyloxy)amino)piperidine-2-carboxylate oxalate, molecular formula is C22H26N2O7. In a Article，once mentioned of 1171080-45-7

Process development work to provide an efficient, robust, and cost-effective manufacturing route to avibactam, a beta-lactamase inhibitor is presented herewith. Aspects of this optimization work include the counterintuitive introduction of a protecting group to effect a difficult urea formation and the use of controlled feed hydrogenation conditions to facilitate an elegant one pot debenzylation and sulfation reaction. Overall, the commercial process delivers avibactam in much improved yield with significant reduction in the environmental footprint.

One of the oldest and most widely used commercial enzyme inhibitors is aspirin, Reference of 1171080-45-7, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 1171080-45-7

Reference：
Piperidine – Wikipedia,
Piperidine | C5H23997N – PubChem

 

Synthetic Route of 1171080-45-7, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.1171080-45-7, Name is (2S,5R)-Benzyl 5-((benzyloxy)amino)piperidine-2-carboxylate oxalate, molecular formula is C22H26N2O7. In a Patent，once mentioned of 1171080-45-7

A cyclic amine compound having a prescribed configuration can be efficiently prepared by reducing an imine derivative in the presence of a sulfonic acid. Specifically, a cyclic amine compound which is substituted with an amino group and a carboxyl group in which both groups are arranged in the trans configuration can be prepared efficiently.

The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 1171080-45-7 is helpful to your research. Synthetic Route of 1171080-45-7

Reference：
Piperidine – Wikipedia,
Piperidine | C5H23999N – PubChem

 

Chemistry is an experimental science, HPLC of Formula: C22H26N2O7, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 1171080-45-7, Name is (2S,5R)-Benzyl 5-((benzyloxy)amino)piperidine-2-carboxylate oxalate

SODIUM SALT OF (2S, 5R)-6-BENZYLOXY-7-OXO-1,6-DIAZA-BICYCLO [3.2.1 ] OCTANE-2-CARBOXYLIC ACID AND ITS PREPARATION

Sodium salt of (2S, 5R)-6-benzyloxy-7-oxo-1,6-diaza-bicyclo[3.2.1]octane-2- carboxylic acid and a process for its preparation is disclosed.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. HPLC of Formula: C22H26N2O7, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 1171080-45-7, in my other articles.

Reference£º
Piperidine – Wikipedia,
Piperidine | C5H23996N – PubChem

 

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1171080-45-7,(2S,5R)-Benzyl 5-((benzyloxy)amino)piperidine-2-carboxylate oxalate,as a common compound, the synthetic route is as follows.

Example 2aBenzyl (2S,5R)-5-[(benzyloxy)amino]piperidine-2-carboxylate ethanedioate (1:1) (50 g, 113.8 mmol) was mixed with a solution of ammonia in methanol (7N, 700 ml) and agitated until the reaction was deemed to be complete. The mixture was filtered to remove ammonium oxalate byproduct, the ammonium oxalate cake was washed with methanol (2¡Á50 ml) and the combined filtrates were concentrated to 250 ml. Toluene (500 ml) was added and the solution was concentrated to 250 ml causing the product to precipitate. Toluene (500 ml) was added, and the mixture was heated to 80 C. and cooled to 0 C. The product was isolated by filtration, washed with methyl tert-butyl ether (MTBE) (100 ml), and dried to yield a white crystalline solid (26.9 g, 108 mmol, 95%).1H NMR (400 MHz, DMSO) deltaH 1.12 (1H, m), 1.27 (1H, m), 1.83 (2H, m), 2.22 (1H, dd), 2.76 (1H, m), 2.89 (1H, dd), 3.14 (1H, dd), 4.58 (2H, s), 6.46 (1H, d), 6.91 (1H, s), 7.09 (1H, s), 7.32 (5H, m).

1171080-45-7, The synthetic route of 1171080-45-7 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; FOREST LABORATORIES HOLDINGS LTD.; US2012/323010; (2012); A1;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem