Category: 112773-90-7

Chen, Jun; Duan, Rong; Chen, Wei; Zhang, Juan; Luo, Xiao-Gang; Li, Jian; Bai, Zheng-Wu published an article on January 31 ,2013. The article was titled 《Enantioseparation properties of the biselector chiral stationary phase derived from amylose tris(phenylcarbamate) and amylose tris(benzoate)》, and you may find the article in Current Analytical Chemistry.SDS of cas: 112773-90-7 The information in the text is summarized as follows:

To study the enantioseparation property of the biselector chiral stationary phase derived from polysaccharide, a new biselector chiral stationary phase was prepared by coating a blend of two amylose derivatives on an aminated silica gel. The blend consisted of amylose tris(phenylcarbamate) and amylose tris(benzoate) at a glucose unit ratio of 1:1 (mol/mol). For the sake of enantioseparation comparison, the corresponding single selector chiral stationary phases were also prepared with the two individual amylose derivatives The enantioseparation ability of these chiral stationary phases was evaluated by using structurally various chiral analytes. The biselector chiral stationary phase showed an overall improved enantioseparation ability in comparison with the two single selector chiral stationary phases. The effect of alcs. in mobile phase on the enantioseparation of the biselector chiral stationary phase is also discussed. After reading the article, we found that the author used (R)-N-(2,6-Dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride(cas: 112773-90-7SDS of cas: 112773-90-7)

(R)-N-(2,6-Dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride(cas: 112773-90-7) belongs to piperidines. Piperidine derivatives are also used in solid-phase peptide synthesis (SPPS) and many degradation reactions. SDS of cas: 112773-90-7

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Category: piperidinesOn November 30, 2007 ,《Development and validation of TLC-densitometric method for resolution and determination of enantiomeric purity of ropivacaine, using different cyclodextrins as chiral selector》 appeared in Current Pharmaceutical Analysis. The author of the article were Taha, Elham A.. The article conveys some information:

A novel economic procedure for stereoselective separation and determination of R(+)- and S(-)- ropivacaine was described using different thin layer chromatog. plates and different cyclodextrins at different temperatures The spots were detected either with iodine vapors or UV lamp 254 nm, followed by densitometric measurements at 262 nm. Comparative study was achieved using different cyclodextrins namely, hydroxypropyl-β-cyclodextrin (HP-β-CD), methyl-β-cyclodextrin (M-β-CD), and dimethyl-β-cyclodextrin (DM-β-CD) as chiral selectors. The mobile phase enabling successful resolution of (±) ropivacaine was acetonitrile: water (17:3 volume/volume) containing 1 mM of DM-β-CD at ambient temperature 25 ± 2°. All variables affecting the resolution, such as concentration of different chiral selectors, temperature, and pH were investigated and the conditions were optimized. The procedure provided a linear response over the concentration range of 1.25-35 μg/spot for determination of R(+)- and S(-)- enantiomers (r = 0.9998, n = 8), (r = 0.9998, n = 6) with acceptable precision (% RSD <1.5) and accuracy (% RE = -1.18 to 2.00). Limits of detection and quantification were found to be 0.29 μg/spot and 0.96 μg/spot for (R) and 0.26 μg/spot and 0.86 μg/spot for (S) resp. The developed method was validated and proved to be robust. Ropivacaine sample solution was found to be stable for one weak in methanol. The proposed method was found to be selective and accurate for identification and quant. determination of enantiomeric purity of ropivacaine in bulk powder and pharmaceutical dosage form. In the experiment, the researchers used (R)-N-(2,6-Dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride(cas: 112773-90-7Category: piperidines)

(R)-N-(2,6-Dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride(cas: 112773-90-7) belongs to piperidines. Piperidine derivatives are also used in solid-phase peptide synthesis (SPPS) and many degradation reactions. Category: piperidines

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

The author of 《Preparation and chiral recognition of new chiral stationary phases derived from cellulose microspheres》 were Jin, Fenfen; Zhang, Juan; Chen, Wei; Fan, Qingchun; Bai, Zhengwu. And the article was published in Wuhan University Journal of Natural Sciences in 2012. Recommanded Product: 112773-90-7 The author mentioned the following in the article:

A new way to prepare cellulose-type chiral stationary phases (CSPs) was established. Cellulose microspheres with a volume-average diameter of 11.5 m were prepared by an emulsion-solidification method. Three new CSPs were obtained by crosslinking the cellulose microspheres with terephthaloyl chloride (TPC), and then modifying the crosslinked microspheres with 4-methylbenzoyl chloride, 3,5-dimethylbenzoyl chloride and 3,5-dichlorobenzoyl chloride, resp. The microspheres and the CSPs were characterized by FTIR, element anal. and scanning electronic microscopy (SEM). The chiral recognition ability of the CSPs was evaluated with HPLC. The chromatog. results demonstrate that the CSP prepared from 3,5-dichlorobenzoyl chloride possesses better chiral recognition ability compared with two other CSPs. In addition to this study using (R)-N-(2,6-Dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride, there are many other studies that have used (R)-N-(2,6-Dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride(cas: 112773-90-7Recommanded Product: 112773-90-7) was used in this study.

(R)-N-(2,6-Dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride(cas: 112773-90-7) belongs to piperidines. Piperidine derivatives are also used in solid-phase peptide synthesis (SPPS) and many degradation reactions. Recommanded Product: 112773-90-7

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

The author of 《Preparation and chiral recognition of new chiral stationary phases derived from cellulose microspheres》 were Jin, Fenfen; Zhang, Juan; Chen, Wei; Fan, Qingchun; Bai, Zhengwu. And the article was published in Wuhan University Journal of Natural Sciences in 2012. Name: (R)-N-(2,6-Dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride The author mentioned the following in the article:

A new way to prepare cellulose-type chiral stationary phases (CSPs) was established. Cellulose microspheres with a volume-average diameter of 11.5 m were prepared by an emulsion-solidification method. Three new CSPs were obtained by crosslinking the cellulose microspheres with terephthaloyl chloride (TPC), and then modifying the crosslinked microspheres with 4-methylbenzoyl chloride, 3,5-dimethylbenzoyl chloride and 3,5-dichlorobenzoyl chloride, resp. The microspheres and the CSPs were characterized by FTIR, element anal. and scanning electronic microscopy (SEM). The chiral recognition ability of the CSPs was evaluated with HPLC. The chromatog. results demonstrate that the CSP prepared from 3,5-dichlorobenzoyl chloride possesses better chiral recognition ability compared with two other CSPs. In addition to this study using (R)-N-(2,6-Dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride, there are many other studies that have used (R)-N-(2,6-Dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride(cas: 112773-90-7Name: (R)-N-(2,6-Dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride) was used in this study.

(R)-N-(2,6-Dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride(cas: 112773-90-7) belongs to piperidines. Piperidine derivatives are also used in solid-phase peptide synthesis (SPPS) and many degradation reactions. Name: (R)-N-(2,6-Dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem