In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 106-52-5, name is 1-Methylpiperidin-4-ol, introducing its new discovery. name: 1-Methylpiperidin-4-ol
The present invention provides a two step esterification process for the synthesis of Propiverine hydrochloride. In the synthetic scheme disclosed herein benzillic acid 1 is directly converted to di-propyl ester ether 7 from the known standard method. The intermediate thus obtained is reacted with N-Methyl 4-hydroxy piperidine in the presence of sodium t-butoxide at room temperature to get Propiverine base 5. This is then finally converted to Propiverine hydrochloride. The process of synthesis provides Propiverine hydrochloride in a very pure form (>99%) with a very good yield. The compound is very useful in treating urinary incontinence.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 106-52-5 is helpful to your research. name: 1-Methylpiperidin-4-ol
Reference:
Piperidine – Wikipedia,
Piperidine | C5H2350N – PubChem