Synthesis of 3H-, 13C3-, and 14C-labeled Sch 727965 was written by Lavey, C. Flader;Hesk, D.;Koharski, D.;Truong, V.;McNamara, P.. And the article was included in Journal of Labelled Compounds and Radiopharmaceuticals in 2011.Category: piperidines This article mentions the following:
The preparation of [3H]Sch 727965 ([3H]I) from unlabeled compound and tritiated water was base catalyzed. Di-Et [13C3]malonate was used to prepare [13C3]Sch 727965 in five steps in 21.8% overall yield. In a similar manner, [14C]Sch 727965 was prepared in five steps from di-Et [2-14C]malonate in 11.1% radiochem. yield. Copyright 漏 2010 John Wiley & Sons, Ltd. In the experiment, the researchers used many compounds, for example, (S)-2-(Piperidin-2-yl)ethanol (cas: 103639-57-2Category: piperidines).
(S)-2-(Piperidin-2-yl)ethanol (cas: 103639-57-2) belongs to piperidine derivatives. Piperidine has a role as a reagent, a protic solvent, a base, a catalyst, a plant metabolite, a human metabolite and a non-polar solvent. Several piperidine alkaloids isolated from natural herbs, were found to exhibit antiproliferation and antimetastatic effects on various types of cancers both in vitro and in vivo for example Piperine, Evodiamine, Matrine, Berberine and Tetrandine.Category: piperidines
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem