Category: 1016258-66-4

Related Products of 1016258-66-4, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.1016258-66-4, Name is 1-tert-Butyl 4-ethyl 4-cyanopiperidine-1,4-dicarboxylate, molecular formula is C14H22N2O4. In a article，once mentioned of 1016258-66-4

The present invention provides a compound of the following formula and salts thereof: Also provided is the use of these compounds as antibacterials, compositions comprising them and processes for their manufacture.

We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 1016258-66-4, and how the biochemistry of the body works.Related Products of 1016258-66-4

Reference：
Piperidine – Wikipedia,
Piperidine | C5H22667N – PubChem

1016258-66-4, 1-tert-Butyl 4-ethyl 4-cyanopiperidine-1,4-dicarboxylate is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

EXAMPLE 26N-((lH-Indol-2-yl)methv?-4-(aminomethv?-l-(7H-pyrrolor2.3-d1pyrimidin-4- yl)piperidine-4-carboxamide26A. 1 -(tert-Butoxycarbonyl)-4-cvanopiperidine-4-carboxylic acid; A solution of lithium hydroxide (21.25 ml, 42.50 mmol) in water was added to a stirred solution of 1-tert-butyl 4-ethyl 4-cyanopiperidine-l,4-dicarboxylate (3g, 10.63 mmol), in THF (42.5 ml) at 250C. The resulting mixture was stirred at 25 0C for 18 hours. The reaction mixture was diluted with Et2O (100 mL), and washed with water (50 mL). The aqueous layers were combined and then acidified with citric acid (IN, 50 mL). The product was extracted into DCM. The organic layer was dried over MgSO4, filtered and evaporated to afford crude product l-(tert-butoxycarbonyl)-4-cyanopiperidine-4-carboxylic acid (2.73 g, 101 %) as a yellow liquid. IH NMR (400.13 MHz, DMSO-d6) delta 1.41 (9H, s), 1.78 – 1.85 (2H, m), 2.04 (2H, d) 2.95 (2H, t), 3.96 (2H, d), 13.9 (IH, s), 1016258-66-4

As the paragraph descriping shows that 1016258-66-4 is playing an increasingly important role.

Reference£º
Patent; ASTEX THERAPEUTICS LIMITED; THE INSTITUTE OF CANCER RESEARCH:ROYAL CANCER HOSPITAL; CANCER RESEARCH TECHNOLOGY LIMITED; ASTRAZENECA AB; WO2008/75110; (2008); A1;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem

1016258-66-4, 1-tert-Butyl 4-ethyl 4-cyanopiperidine-1,4-dicarboxylate is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

To an ice-cold solution of O1-tert-butyl O4-ethyl 4-cyanopiperidine-1,4-dicarboxylate (0.4 g, 1.41 mmol) in 1,4-dioxane (10 mL) was added HCl-dioxane (4 M, 5 mL) solution. The resulting mixture was stirred at rt for 30 minutes. After completion of reaction (by TLC), solvent was evaporated to obtain the product as a solid (0.28 g). MS: 183.27 [M+H]+.

1016258-66-4, The synthetic route of 1016258-66-4 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; BIOTA EUROPE LTD.; US2012/88750; (2012); A1;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem