Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent， Product Details of 56346-57-7, Which mentioned a new discovery about 56346-57-7
Introducing purine bases to P2-ligands might enhance the potency of Human Immunodeficiency Virus-1 (HIV-1) protease inhibitory because of the carbonyl and NH groups promoting the formation of extensive H-bonding interactions. In this work, thirty-three compounds are synthesized and evaluated, among which inhibitors 16a, 16f and 16j containing N-2-(6-substituted-9H-purin-9-yl)acetamide as the P2-ligands along with 4-methoxylphenylsulfonamide as the P2?-ligand, display potent inhibitory effect on the activity of HIV-1 protease with IC50 43 nM, 42 nM and 68 nM in vitro, respectively.
Because enzymes can increase reaction rates by enormous factors and tend to be very specific, Product Details of 56346-57-7, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 56346-57-7
Reference：
Piperidine – Wikipedia,
Piperidine | C5H15468N – PubChem