A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, Safety of 2-Oxa-8-azaspiro[4.5]decane hydrochloride, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 479195-19-2, Name is 2-Oxa-8-azaspiro[4.5]decane hydrochloride, molecular formula is C8H16ClNO. In a Patent, authors is £¬once mentioned of 479195-19-2
4-quinazoline amine derivatives and their use (by machine translation)
A 4-quinazoline amine derivative as represented by formula (1), a pharmaceutical composition comprising the derivative, and an application thereof in preparing medicine for curing cancer. The cancer is a drug-resistant cancer, preferably a cancer resisting an EGFR reversible inhibitor, and more preferably, a cancer resisting gefitinib, erlotinib or lapatinib; alternatively, the cancer carries EGFR mutation.
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Reference£º
Piperidine – Wikipedia,
Piperidine | C5H10763N – PubChem