Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent， category: piperidines, Which mentioned a new discovery about 170011-57-1
A synthesis of methyl 3-(2-methoxy-4-pyridyl)propionate (4), a key intermediate in the synthesis of the potent and long-acting histamine H2-receptor antagonist SK&F 93574 (3), is described.The key steps in the synthesis of compound (4) are a Claisen ester condensation to give the intermediate (16) and a subsequent reduction step to give the ester (4).The reduction was found to be difficult and our investigations are described.In addition, alternative, but unsuccesful, approaches to the desired pyridylpropionate (4) are discussed.
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Reference：
Piperidine – Wikipedia,
Piperidine | C5H22366N – PubChem