Chemistry is an experimental science, COA of Formula: C10H19NO2, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 138007-24-6, Name is tert-Butyl piperidine-4-carboxylate
Optimization of ketone-based P2Y12 receptor antagonists as antithrombotic agents: Pharmacodynamics and receptor kinetics considerations
Modification of a series of P2Y12 receptor antagonists by replacement of the ester functionality was aimed at minimizing the risk of in vivo metabolic instability and pharmacokinetic variability. The resulting ketones were then optimized for their P2Y12 antagonistic and anticoagulation effects in combination with their physicochemical and absorption profiles. The most promising compound showed very potent antiplatelet action in vivo. However, pharmacodynamic-pharmacokinetic analysis did not reveal a significant separation between its anti-platelet and bleeding effects. The relevance of receptor binding kinetics to the in vivo profile is described.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. COA of Formula: C10H19NO2, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 138007-24-6, in my other articles.
Reference£º
Piperidine – Wikipedia,
Piperidine | C5H11522N – PubChem