Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels. 105812-81-5, Name is (3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine, molecular formula is C13H18FNO. In an article, author is Mohamadpour, Farzaneh,once mentioned of 105812-81-5, Recommanded Product: 105812-81-5.
Imin-based synthesis of polyfunctionalized dihydro-2-oxypyrroles catalyzed by glycine amino acid via tandem Michael-Mannich cyclocondensation reaction under ambient temperature
An efficient and mild synthetic route to the convenient one-pot preparation of polyfunctionalized dihydro-2-oxypyrroles has been developed and catalyzed via glycine amino acid as a natural bio-based and biodegradable catalyst using imin-based four condensation domino reaction of amines, dialkyl acetylenedicarboxylates and formaldehyde via tandem Michael-Mannich cyclocondensation reaction under ambient temperature. The reactions complete in less time, but the products are obtained in outstanding yields. This environmentally friendly method includes the noticeable properties such as bio-based and green catalyst, direct workup without column chromatographic separation, cost-effective, mild and simple synthesis, one-pot procedure and high atom economy.
Interested yet? Keep reading other articles of 105812-81-5, you can contact me at any time and look forward to more communication. Recommanded Product: 105812-81-5.
Reference:
Piperidine – Wikipedia,
,Piperidine | C5H11N – PubChem