Pd-PEPPSI-IPent: Low-Temperature Negishi Cross-Coupling for the Preparation of Highly Functionalized, Tetra-ortho-Substituted Biaryls was written by Calimsiz, Selcuk;Sayah, Mahmoud;Mallik, Debasis;Organ, Michael G.. And the article was included in Angewandte Chemie, International Edition in 2010.HPLC of Formula: 331767-56-7 This article mentions the following:
Pd-PEPPSI-IPent catalyzed the Negishi cross-coupling reactions of arylzinc halides with aryl/heteroaryl bromides or chlorides for the synthesis of very challenging and structurally diverse biaryl compounds In the experiment, the researchers used many compounds, for example, tert-Butyl 4-(6-bromopyridin-2-yl)piperazine-1-carboxylate (cas: 331767-56-7HPLC of Formula: 331767-56-7).
tert-Butyl 4-(6-bromopyridin-2-yl)piperazine-1-carboxylate (cas: 331767-56-7) belongs to piperazine derivatives. The piperazine scaffold is often found in biologically active compounds in different therapeutic areas. These therapeutic areas include antifungals, antidepressants, antivirals, and serotonin receptor (5-HT) antagonists/agonists. Piperazine is an anthelminthic especially useful in the treatment of partial intestinal obstruction caused by Ascaris worms, which is a condition primarily seen in children. Piperazine hydrate and piperazine citrate are the main anthelminthic piperazines.HPLC of Formula: 331767-56-7
Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics