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Nickel-catalyzed carboxylation of aryl and heteroaryl fluorosulfates using carbon dioxide
The development of efficient and practical methods to construct carboxylic acids using CO2 as a C1 synthon is of great importance. Nickel-catalyzed carboxylation of aryl fluorosulfates and heteroaryl fluorosulfates with CO2 is described, affording arene carboxylic acids with good to excellent yields under mild conditions. In addition, a one-pot phenol fluorosulfation/carboxylation is developed.
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Reference£º
Piperidine – Wikipedia,
Piperidine | C5H22363N – PubChem