79421-45-7,With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.79421-45-7,1-(4-Nitrophenyl)piperidin-4-ol,as a common compound, the synthetic route is as follows.
Step: 3A-2Synthesis of l-(4-Amino-phProcedure:Pd-C (150mg) was added to a stirred solution of l-(4-Nitro-phenyl)-piperidin-4-ol (1.4g, 0.00630mol) in MeOH (5ml) under nitrogen atmosphere and then hydrogen gas was passed. The reaction was monitored by the TLC (10% MeOH: CHC13). The resultant was filtered and concentrated to afford 1.15g (96% yield) of l-(4-Amino-phenyl)-piperidin-4-ol.
The synthetic route of 79421-45-7 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; AURIGENE DISCOVERY TECHNOLOGIES LIMITED; SENGUPTA, Saumitra; RAJAGOPALAN, Srinivasan; BELAVAGI, Ningaraddi; RAMACHANDRA, Muralidhara; WO2012/59932; (2012); A1;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem