Brief introduction of 78619-84-8

One of the oldest and most widely used commercial enzyme inhibitors is aspirin, Application of 78619-84-8, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 78619-84-8

Application of 78619-84-8, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.78619-84-8, Name is 4,4′-Bipiperidine dihydrochloride, molecular formula is C10H22Cl2N2. In a Article£¬once mentioned of 78619-84-8

[35S]GTPgammaS binding studies of amphiphilic drugs-activated Gi proteins: A caveat

This paper documents a serious problem met during the testing of Gi protein-activating properties of a new series of synthetic compounds by measuring the induced binding of [35S]GTPgammaS to different subtypes of Gi protein. The problem arose from the strong affinity between [35S]GTPgammaS and the tested compounds, that are characterized by several (2-4) positive charges and high lipophilicity. Apparently, such affinity yields insoluble, labelled complexes that, also in the absence of Gi protein, are retained on the filters and give rise to false positive results.

One of the oldest and most widely used commercial enzyme inhibitors is aspirin, Application of 78619-84-8, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 78619-84-8

Reference£º
Piperidine – Wikipedia,
Piperidine | C5H19977N – PubChem