With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.5810-56-0,4-Acetamidopiperidine,as a common compound, the synthetic route is as follows.,5810-56-0
2.1 b lambda/-[1-(4-{2-[2-Oxo-4-(thiophen-2-ylmethoxy)-2/-/-pyridin-1-yl]-ethyl}-benzyl)-piperidin-4-yl]- acetamide To 45 mg (0.13 mmol) 1-[2-(4-hydroxymethyl-phenyl)-ethyl]-4-(thiophen-2-ylmethoxy)-1 /-/- pyridin-2-one (example 2.1 a) in 3.0 mL DCM is added 55 muL triethylamine (0.40 mmol) and subsequently 20 muL (0.26 mmol) methanesulfonyl chloride at RT. The reaction mixture is stirred 1 h at RT and then 37 mg (0.40 mmol) lambda/-piperidin-4-yl-acetamide is added. The mixture is stirred overnight at RT and is directly added to a reverse HPLC for purification (Zorbax stable bond, C18, 7 mum;water (0.15 % formic acid)/acetonitrile 95:5 to 10:90). Yield: 22 mg (36% of theory) ESI Mass spectrum: [M+H]+ = 466
As the paragraph descriping shows that 5810-56-0 is playing an increasingly important role.
Reference：
Patent; BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG; WO2008/22979; (2008); A1;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem