503614-92-4, 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
503614-92-4, 12.5 g (27.1 mmol) of substance of formula 11c obtained in example 10 is suspended in DMA, then under argon atmosphere 8.0 g (49.3 mmol) of carbonyldiimidazole (CDI) is added, and the mixture is heated to 60 C, and it is maintained at this temperature for 1 hour. Then 18.8 mL (13.7 g, 136 mmol) of triethylamine and 6.25 g (81 mmol) of ammonium acetate are added to the mixture. The stirring is continued for 1 hour. Water is added to the mixture and the suspension is slowly cooled to 20 C. The precipitated substance is filtered off and washed. After drying 11.36 g (24.7 mmol, 91%) of off-white substance is obtained. Mp.: 236-238 C.
The synthetic route of 503614-92-4 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; EGIS GYOGYSZERGYAR ZRT.; MRAVIK, Andras; NAGY, Tamas; FARAGO, Janos; VOLK, Balazs; LUKACS, Gyula; NEMETH, Gabor; CZOBORNE HATVARI, Ilona; SLEGEL, Peter; CSONKA-KIS, Gy?z?; KORMANY, Robert; (39 pag.)WO2016/20711; (2016); A1;,
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