The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. 4727-72-4, Name is 1-Benzylpiperidin-4-ol, SMILES is C2=C(CN1CCC(O)CC1)C=CC=C2, in an article , author is Rafiq, Kiran, once mentioned of 4727-72-4, Application In Synthesis of 1-Benzylpiperidin-4-ol.
Some novel piperidine analogues having strong alpha glucosidase inhibition
The idea of this study is based on the marvelous fact of nojirimycin and deoxy nojirimycin, naturally occurring from piperidine class and having their role as alpha glucosidase inhibitors. In the present work some hydroxy piperidine analogues have been synthesized and analysed for their hypoglycemic effect through glucosidase inhibition owing to the structural resemblance with nojirimycin. The activity was done by spectral absorbance analysis using acarbose as standard. Two analogues (I & IV) were found to pose excellent activity having 87.4 and 54.7% inhibition respectively, hence strengthening the idea of studying piperidine analogiues as glucosidase inhibitors due to structural similarity with nojirimycin.
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Reference:
Piperidine – Wikipedia,
,Piperidine | C5H11N – PubChem