4606-65-9, 3-(Hydroxymethyl)piperidine is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Scheme 6, step B. To a solution ofpiperidin-3-ylmethanol (2.10 g, 0.018 mol) inCHzCh (20 mL) is added triethylamine (5.53 g, 0.0547 mol) followed by tbutyldimethylchlorosilane( 4.127 g, 0.0275 mol) and the reaction mixture is stirred atroom temperature. After 24 hours, the reaction mixture is washed with water, saturated solution ofNaHC03, and brine. The combined organic layers are combined and dried25over sodium sulfate, filtered, and concentrated under reduced pressure. The resultingresidue is purified by flash chromatography (silica gel) over a gradient using 0-10%MeOH in dichloromethane to afford the title compound (2.50 g, 60 %). Mass spectrum(m/z): 231.2 (M+1)., 4606-65-9
The synthetic route of 4606-65-9 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; ELI LILLY AND COMPANY; BLANCO-PILLADO, Maria-Jesus; VETMAN, Tatiana Natali; FISHER, Matthew Joseph; KUKLISH, Steven Lee; WO2014/4230; (2014); A1;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem