With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.189442-92-0,1-Boc-4-Formyl-4-methylpiperidine,as a common compound, the synthetic route is as follows.
Step 3. Synthesis of 4-aminomethyl-1-t-butoxycarbonyl-4-methylpiperidine To a solution of 367 mg of N-t-butoxycarbonyl-4-methylpiperidine-4-carbaldehyde in 5 ml of methanol, 1.2 g of ammonium acetate and 130 mg of sodium cyanoborohydride, followed by stirring for 1 hour at room temperature. The reaction mixture was diluted with chloroform, washed sequentially with a 3N sodium hydroxide aqueous solution and brine, and dried over anhydrous sodium sulfate. The solvent was distilled off under reduced pressure to give the title compound., 189442-92-0
189442-92-0 1-Boc-4-Formyl-4-methylpiperidine 22248051, apiperidines compound, is more and more widely used in various fields.
Reference£º
Patent; Banyu Pharmaceutical Co Ltd; US6140333; (2000); A;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem