Brief introduction of 177-11-7

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Convenient strecker reactions of piperidine derivatives with cyclic ketones under aqueous conditions

Strecker reactions convenient for the preparation of piperidinyl acetonitrile compounds under aqueous conditions are described. The use of TsOH¡¤H2O is the key to afford the desired products in good and reproducible yield. Copyright Taylor & Francis Group, LLC.

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Reference£º
Piperidine – Wikipedia,
Piperidine | C5H7475N – PubChem