With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.160357-94-8,1-Acetyl-4-aminopiperidine,as a common compound, the synthetic route is as follows.
Step 3 Preparation of N-Acetyl-1-(3-(4-Fluorophenoxy)propyl)-4-Aminopiperidine N-Acetyl-4-aminopiperidine (5.80 g, 41 mmol) and O-(p-toluenesulfonyl)-3-(4-fluorophenoxy)propanol (13.24 g, 41 mmol) were converted to the title compound by the procedure of Preparation 2, Step 3 to give a crude product which was recrystallized from ethyl acetate to give 7.82 g of the title compound. Yield: 65%. m.p. 134 C.-136 C. EA calculated for C16 H23 N2 O2 F: C, 65.28; H, 7.88; N, 9.52. Found: C, 65.49; H, 7.91; N, 9.54. MS(FD) M+1 295., 160357-94-8
160357-94-8 1-Acetyl-4-aminopiperidine 4962477, apiperidines compound, is more and more widely used in various fields.
Reference£º
Patent; Eli Lilly and Company; US6069152; (2000); A;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem