Brief introduction of 108-26-9

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 108-26-9. SDS of cas: 108-26-9.

Chemistry, like all the natural sciences, SDS of cas: 108-26-9, begins with the direct observation of nature— in this case, of matter.108-26-9, Name is 3-Methyl-1H-pyrazol-5(4H)-one, SMILES is O=C1CC(C)=NN1, belongs to piperidines compound. In a document, author is Zhang, Juzheng, introduce the new discover.

Developing a Novel Gold(III) Agent to Treat Glioma Based on the Unique Properties of Apoferritin Nanoparticles: Inducing Lethal Autophagy and Apoptosis

Effective delivery of anticancer agents across the blood-brain barrier (BBB) required innovative strategies to achieve glioma regression. To resolve this problem, we proposed to develop a metal agent that target and treat glioma based on the unique property of apoferritin (AFt) nanoparticles (NPs). Thus, we synthesized a series of Au(III) 3-(4-metyl piperidine)-thiosemicarbazides compounds and analyzed their structure-activity relationships, obtaining a Au agent (C6) with remarkable cytotoxicity in glioma. Moreover, we confirmed that C6 kills glioma cells by inducing lethal autophagy and apoptosis. Importantly, our results revealed that the successfully constructed apoferritin-C6 NPs (AFt-C6 NPs) can effectively cross the BBB, inhibit glioma growth, and selectively accumulate in tumors.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 108-26-9. SDS of cas: 108-26-9.

Reference:
Piperidine – Wikipedia,
,Piperidine | C5H11N – PubChem