Brenna, Elisabetta et al. published their research in Advanced Synthesis & Catalysis in 2018 | CAS: 219543-09-6

4-Acetamido-2,2,6,6-tetramethyl-1-oxopiperidinium Tetrafluoroborate (cas: 219543-09-6) belongs to piperidine derivatives. The piperidine moiety constitutes an important building block for the synthesis of a variety of bioactive natural products, alkaloids and other drugs. Piperidine derivatives bearing a masked aldehyde function in the 蔚-position are easily transformed into quinolizidine compounds through intramolecular reductive amination.Recommanded Product: 219543-09-6

Chemo-Enzymatic Oxidative Rearrangement of Tertiary Allylic Alcohols: Synthetic Application and Integration into a Cascade Process was written by Brenna, Elisabetta;Crotti, Michele;De Pieri, Matteo;Gatti, Francesco G.;Manenti, Gabriele;Monti, Daniela. And the article was included in Advanced Synthesis & Catalysis in 2018.Recommanded Product: 219543-09-6 This article mentions the following:

A chemo-enzymic catalytic system, comprised of Bobbitt’s salt and laccase from Trametes versicolor, allowed the [1,3]-oxidative rearrangement of endocyclic allylic tertiary alcs. into the corresponding enones under an Oxygen atm. in aqueous media. The yields were in most cases quant., especially for the cyclopent-2-en-1-ol or the cyclohex-2-en-1-ol substrates without an electron withdrawing group (EWG) on the side chain. Transpositions of macrocyclic alkenols or tertiary alcs. bearing an EWG on the side chain were instead carried out in acetonitrile by using an immobilized laccase preparation Dehydro-Jasmone, dehydro-Hedione, dehydro-Muscone and other fragrance precursors were directly prepared with this procedure, while a synthetic route was developed to easily transform a cyclopentenone derivative into trans-Magnolione and dehydro-Magnolione. The rearrangement of exocyclic allylic alcs. was tested as well, and a dynamic kinetic resolution was observed: 伪,尾-unsaturated ketones with (E)-configuration and a high diastereomeric excess were synthesized. Finally, the 2,2,6,6-tetramethyl-1-piperidinium tetrafluoroborate (TEMPO+BF4–)/laccase catalyzed oxidative rearrangement was combined with the ene-reductase/alc. dehydrogenase cascade process in a one-pot three-step synthesis of cis or trans 3-methylcyclohexan-1-ol, in both cases with a high optical purity. In the experiment, the researchers used many compounds, for example, 4-Acetamido-2,2,6,6-tetramethyl-1-oxopiperidinium Tetrafluoroborate (cas: 219543-09-6Recommanded Product: 219543-09-6).

4-Acetamido-2,2,6,6-tetramethyl-1-oxopiperidinium Tetrafluoroborate (cas: 219543-09-6) belongs to piperidine derivatives. The piperidine moiety constitutes an important building block for the synthesis of a variety of bioactive natural products, alkaloids and other drugs. Piperidine derivatives bearing a masked aldehyde function in the 蔚-position are easily transformed into quinolizidine compounds through intramolecular reductive amination.Recommanded Product: 219543-09-6

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem