Bregman, Howard et al. published their research in Organic Letters in 2006 | CAS: 25560-00-3

3-(2-Methylpiperidin-1-yl)propan-1-amine (cas: 25560-00-3) belongs to piperidine derivatives.Piperidine is a key saturated heterocyclic scaffold found in several of the top-selling small molecule pharmaceuticals and natural alkaloids, with a diverse range of biological activities. Fluorinated piperidines are also the subject of continued interest in medicinal chemistry, for example in the synthesis of selective dipeptidyl peptidase II (DPP II) inhibitors. Piperidine derivatives are also used in solid-phase peptide synthesis (SPPS) and many degradation reactions.Quality Control of 3-(2-Methylpiperidin-1-yl)propan-1-amine

Ruthenium half-sandwich complexes as protein kinase inhibitors: An N-succinimidyl ester for rapid derivatizations of the cyclopentadienyl moiety was written by Bregman, Howard;Meggers, Eric. And the article was included in Organic Letters in 2006.Quality Control of 3-(2-Methylpiperidin-1-yl)propan-1-amine This article mentions the following:

Racemic and metal-chiral ruthenium half-sandwich pyrido[2,3-a]carbazole complexes I bearing carboxamide substituents in the cyclopentadienyl ring were prepared and tested for Pim-1 and GSK-3伪 protein kinase inhibition. Reaction of cyclopentadienylcarboxylic ester complex, [(MeCN)2(CO)Ru(畏5-C5H4CO2CH2CH2TMS)] with 6-R-pyrido[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H,12H)-dione (HL1, R = TBS) afforded ruthenium half-sandwich [(L1-N1,N12)(CO)Ru(畏5-C5H4CO2CH2CH2TMS)] (10a), which after deprotection yields the carboxylic acid [(L-N1,N12)(CO)Ru(畏5-C5H4CO2H)] [11; L = pyrido[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H,12H)-dione anion]; esterification with N-hydroxysuccinimide gave the active ester, [(L-N1,N12)(CO)Ru(畏5-C5H4CO2R1)] (4, R1 = 2,5-dioxopyrrolidin-1-yl). Amidation of 4 with a library of amines RNH2 afforded the amides, [(L-N1,N12)(CO)Ru(畏5-C5H4CONHR)] (2, 3, 12–24). The obtained amides were tested for their pharmacol. properties, by inhibition assay of Pim-1 and GSK-3伪 protein kinases. The organometallic Pim-1 and GSK-3 inhibitors with improved potencies and kinase selectivities were identified. In the experiment, the researchers used many compounds, for example, 3-(2-Methylpiperidin-1-yl)propan-1-amine (cas: 25560-00-3Quality Control of 3-(2-Methylpiperidin-1-yl)propan-1-amine).

3-(2-Methylpiperidin-1-yl)propan-1-amine (cas: 25560-00-3) belongs to piperidine derivatives.Piperidine is a key saturated heterocyclic scaffold found in several of the top-selling small molecule pharmaceuticals and natural alkaloids, with a diverse range of biological activities. Fluorinated piperidines are also the subject of continued interest in medicinal chemistry, for example in the synthesis of selective dipeptidyl peptidase II (DPP II) inhibitors. Piperidine derivatives are also used in solid-phase peptide synthesis (SPPS) and many degradation reactions.Quality Control of 3-(2-Methylpiperidin-1-yl)propan-1-amine

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem