Bhavanam, Lourdu Rani published the artcileSynthesis, Characterization, Anticancer and Antimicrobial Activity Studies of Novel Isomeric 2,4-Disubstituted Ureide Derivatives of Pyrimidinopiperidines, COA of Formula: C10H20N2O2, the main research area is pyrimidinopiperidine ureide preparation anticancer antimicrobial.
A series of isomeric ureide derivatives of novel 2,4-disubstituted pyrimidinopiperidines, e.g., I were synthesized starting from 2,4-dichloropyrimidine. All the final products were purified on silica and characterized by spectral anal. Both the 2,4-disubstituted pyrimidinopiperidines were analyzed for their in vitro anticancer activity on the cell lines HCT116, MIA-PaCa2 and MDA-MB 231 by using MTT cell proliferation assay. Further, the antimicrobial studies were carried out against different bacterial and fungal strains by employing cup plate method. These compounds showed significant anticancer activity on tested three cancer cell lines and exhibited potent antimicrobial activity in tested strains of bacteria and fungi.
ChemistrySelect published new progress about Antibacterial agents. 73874-95-0 belongs to class piperidines, name is tert-Butyl piperidin-4-ylcarbamate, and the molecular formula is C10H20N2O2, COA of Formula: C10H20N2O2.
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem