A general method for the α-acyloxylation of carbonyl compounds was written by Beshara, Cory S.;Hall, Adrian;Jenkins, Robert L.;Jones, Kerri L.;Jones, Teyrnon C.;Killeen, Niall M.;Taylor, Paul H.;Thomas, Stephen P.;Tomkinson, Nicholas C. O.. And the article was included in Organic Letters in 2005.Name: 1-Tosylpiperidin-4-one This article mentions the following:
A simple, one-pot method for the α-acyloxylation of carbonyl compounds that proceeded at room temperature in the presence of both moisture and air has been developed. Treatment of a variety of aldehydes and both cyclic and acyclic ketones with N-methyl-O-benzoylhydroxylamine hydrochloride provided the α-functionalized product in good isolated yield. The transformation was tolerant of a wide range of functional groups and, significantly, was regiospecific in the discrimination of secondary over primary centers in the case of nonsym. substrates. In the experiment, the researchers used many compounds, for example, 1-Tosylpiperidin-4-one (cas: 33439-27-9Name: 1-Tosylpiperidin-4-one).
1-Tosylpiperidin-4-one (cas: 33439-27-9) belongs to piperidine derivatives. The piperidine structural motif is present in numerous natural alkaloids. These include piperine, which gives black pepper its spicy taste. Some chemotherapeutic agents have piperidine moiety within their structure, foremost among them, vinblastine and raloxifene.Name: 1-Tosylpiperidin-4-one
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem