Bellomo, Piero published the artcileSynthesis and antibacterial activity of some derivatives of tolypomycinone. Relation between structure and activity in ansamycins, COA of Formula: C7H16N2, the publication is Journal of Medicinal Chemistry (1977), 20(10), 1287-91, database is CAplus and MEDLINE.
A series of 29 3-aminotolypomycinone derivatives and 3,16-diamino-16,17-dihydrotolypomycinone derivatives were prepared by addition of a primary or secondary amine to tolypomycinone, and 3-(methylamino)-16,17-dihydrotolypomycinone was prepared by addition of MeNH2 to 16,17-dihydrotolypomycinone. One of the most active compounds, 3-[2-(N-morpholyl)ethylamino]tolypomycinone (I), had enhanced stability and prolonged activity against Staphylococcus aureus in acid and alk. solutions as compared to tolypomycin Y. In vitro tests showed high antibacterial activity for several compounds against S. aureus and 3 strains of gram-neg. bacteria. Structure-activity relations are discussed.
Journal of Medicinal Chemistry published new progress about 14613-37-7. 14613-37-7 belongs to piperidines, auxiliary class Piperidine,Amine, name is (1-Methylpiperidin-3-yl)methanamine, and the molecular formula is C7H16N2, COA of Formula: C7H16N2.
Referemce:
https://en.wikipedia.org/wiki/Piperidine,
Piperidine | C5H11N – PubChem