Piperidine was first reported in 1850 by the Scottish chemist Thomas Anderson and again, independently, in 1852 by the French chemist 84358-13-4, formula is C11H19NO4, Name is 1-(tert-Butoxycarbonyl)piperidine-4-carboxylic acid. Auguste Cahours, who named it. Both of them obtained piperidine by reacting piperine with nitric acid. Related Products of 84358-13-4.
Bao, Qiao-Fei;Li, Ming;Xia, Yu;Wang, Yu-Zhao;Zhou, Zhao-Zhao;Liang, Yong-Min research published 《 Visible-Light-Mediated Decarboxylative Radical Addition Bifunctionalization Cascade for the Production of 1,4-Amino Alcohols》, the research content is summarized as follows. A photocatalytic decarboxylative radical addition bifunctionalization cascade for the synthesis of functionalized alcs. e.g., 2-(cyclohexylmethyl)-2-methylpent-4-enoic acid is described. The catalytic cycle is completed through single-electron transfer. The advantages of this reaction are the com. available materials, wide functional group compatibility, and mild conditions. Notably, some amino acids and bioactive carboxylic acids e.g., gemfibrozil can provide corresponding products e.g., 7-(2,5-dimethylphenoxy)-4,4-dimethyl-1,2,2-triphenylheptan-1-ol in moderate to good yields, reflecting the potential value in drug development.
Related Products of 84358-13-4, N-BOC-piperidine-4-carboxylic acid, also known asN-Boc-isonipecotic acid , is a useful research compound. Its molecular formula is C11H19NO4 and its molecular weight is 229,28 g/mole. The purity is usually 95%.
N-Boc-isonipecotic acid is a potent antitumor agent that has been clinically shown to be effective against leukemia and lymphoma. It has potent antibacterial activity against Gram-positive bacteria such as Staphylococcus aureus and Streptococcus pyogenes. N-Boc-isonipecotic acid binds to the gyrase enzyme, which is used by these bacteria to maintain the integrity of their DNA, inhibiting protein synthesis and cell division. This drug also has anti-inflammatory properties. N-Boc-isonipecotic acid inhibits prostaglandin synthesis in cells, which may be due to its ability to inhibit the production of tumor necrosis factor α (TNFα) in macrophages., 84358-13-4.
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem