Chemistry is an experimental science, Computed Properties of C6H14N2, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 41838-46-4, Name is 4-Amino-1-methylpiperidine
Tafamidis, 1, a potent transthyretin kinetic stabilizer, weakly inhibits the gamma-secretase enzyme in vitro. We have synthesized four amide derivatives of 1. These compounds reduce production of the Abeta peptide in N2a695 cells but do not inhibit the gamma-secretase enzyme in cell-free assays. By performing fluorescence correlation spectroscopy, we have shown that TTR inhibits Abeta oligomerization and that addition of tafamidis or its amide derivative does not affect TTR’s ability to inhibit Abeta oligomerization. The piperazine amide derivative of tafamidis (1a) efficiently penetrates and accumulates in mouse brain and undergoes proteolysis under physiological conditions in mice to produce tafamidis.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Computed Properties of C6H14N2, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 41838-46-4, in my other articles.
Reference：
Piperidine – Wikipedia,
Piperidine | C5H1889N – PubChem