In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 2213-43-6, name is 1-Aminopiperidine, introducing its new discovery. name: 1-Aminopiperidine
The reduction of selected nitrosamines by aqueous TiCl3 has been investigated.In general, aliphatic nitrosamines were converted in good yield to the corresponding hydrazines, with little overreduction to the amines.Reaction proceeded rapidly at room temperature in both alkaline and acidic media.A variety of N,N-dialkylhydrazines have been isolated by using the TiCl3 method, which compares favorably with previously reported procedures for preparatively converting nitrosamines to hydrazines.In the reduction of N-nitroso-N-methylaniline, the proportion of amine in the product increased significantly as the pH of the reaction mixture was lowered, presumably reflecting the known instability of arylalkylnitrosamines in strong acid, coupled with a ready reducibility of the corresponding Fischer-Hepp intermediates; some tendency toward reductive cleavage of the N-aryl-N-alkylhydrazine’s N-N-bond was also noted.Reduction of an alpha-nitrosamino ether gave the monoalkylhydrazine as the major product, while all other reducing agents studied converted this starting material chiefly to a mixture of primary and secondary amines.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 2213-43-6 is helpful to your research. name: 1-Aminopiperidine
Reference：
Piperidine – Wikipedia,
Piperidine | C5H660N – PubChem