A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 622-26-4, Name is 2-(Piperidin-4-yl)ethanol, molecular formula is C7H15NO. In an article, author is Hussein, A. M.,once mentioned of 622-26-4, Category: piperidines.
beta-Oxo Anilides in Heterocyclic Synthesis: Novel Synthesis of Pyridazinones, Pyrazolopyridazines and Cinnolines
COMPOUND 1 coupled smoothly with aromatic diazonium salts to yield the corresponding arylhydrazones 2a-d. Compounds 2a-d condensed with DMF-DMA in refluxing xylene to yield the pyridazinones 3a-d. Compounds 3a-d were also established based on its further reaction with some active methylene reagents and some nucleophilic reagents. So, reactions of 3a, b with malononitrile in refluxing ethanolic piperidine afforded arylidinemalononitrile 4a,b. The pyridazinone derivatives 3a, b reacted with hydrazine hydrate to afford the hydrazine derivatives 5a, b. When 3a,b were fused with hydrazine hydrate without solvent, the pyrazolo[4,3-c]-pyridazines 6a,b were obtained. Compounds 6a, b were also obtained when compounds 5a, b melt over melting point for short time. Condensation of 2a, b with ethyl cyanoacetate yield 7a, b. Similarly, reactions of 2a,b with 1 mole of malononitrile afforded the pyridazine derivatives 8a,b. While, two moles of malononitrile reacted with 2a, b in the same experimental conditions to yield the cinnoline derivative 9a, b. Reactions of pyridazine 8a,b with 1 mole of malononitrile afforded 9. Compound 2b was reacted with a mixture of arylidinemalononitrile and acrylonitrile to yield product formulated as triazole moieties 12a, b. Similarly compound 2b was reacted with a mixture of maleic anhydride and acrylonitrile in the same above experimental conditions to give 13. Also, reactions of 2b with hydroxylamine hydrochloride yield 14.
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Reference:
Piperidine – Wikipedia,
,Piperidine | C5H11N – PubChem