In an article, author is Sharghi, Hashem, once mentioned the application of 3040-44-6, Safety of 1-(2-Hydroxyethyl)piperidine, Name is 1-(2-Hydroxyethyl)piperidine, molecular formula is C7H15NO, molecular weight is 129.2001, MDL number is MFCD00006512, category is piperidines. Now introduce a scientific discovery about this category.
Heterogeneous AlPO4(SO3H) nanosheets: novel catalyst for the multi-component synthesis of quinazolinones and highly functionalized piperidines
Nanosheets AlPO4(SO3H) as a highly active solid acid catalyst were prepared and characterized. The morphology of obtained catalyst exhibited nanosheets with similar to 25-35 nm thickness. The heterogeneous nanocatalyst was characterized by FT-IR, EDX, and FE-SEM analysis. The nanosulfonated-AlPO4 were found useful for cyclization synthesis of highly functionalized piperidines and quinazolinones derivatives in good to excellent yields. Notable features include easy and quick isolation of products, ease of handling of the catalyst at low cost, no need to purify with column chromatography, and mild reaction conditions. In addition, according to the literature, another significant feature of our method for quinazolinone synthesis is that structurally diverse molecules were synthesized. Finally, the newly developed catalytic systems avoid the use of toxic metal catalysts and were reused up to 5 times without a noticeable their catalytic activity.
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Reference:
Piperidine – Wikipedia,
,Piperidine | C5H11N – PubChem