Archives for Chemistry Experiments of 879275-33-9

Because enzymes can increase reaction rates by enormous factors and tend to be very specific, Safety of (R)-tert-Butyl (piperidin-3-ylmethyl)carbamate, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 879275-33-9

Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent， Safety of (R)-tert-Butyl (piperidin-3-ylmethyl)carbamate, Which mentioned a new discovery about 879275-33-9

A series of chiral lactam carboxamides of aminomethylpiperidine were synthesized and investigated for the collagen induced in vitro anti-platelet efficacy and collagen plus epinephrine induced in vivo pulmonary thromboembolism. The compound 31a (30 muM/kg) displayed a remarkable antithrombotic efficacy (60% protection) which was sustained for more than 24 h and points to its excellent bioavailability. The compounds 31a (IC50 = 6.6 muM) and 32a (IC50 = 37 muM), as well as their racemic mixture 28i (IC50 = 16 muM) significantly inhibited collagen-induced human platelet aggregation in vitro. Compound 34c displayed dual mechanism of action against both collagen (IC50 = 3.3 muM) and U46619 (IC50 = 2.7 muM) induced platelet aggregation. The pharmacokinetic study of 31a indicated very faster absorption, prolonged and constant systemic exposure and thereby exhibiting better therapeutic response.

Because enzymes can increase reaction rates by enormous factors and tend to be very specific, Safety of (R)-tert-Butyl (piperidin-3-ylmethyl)carbamate, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 879275-33-9

Reference：
Piperidine – Wikipedia,
Piperidine | C5H16740N – PubChem