Synthetic Route of 50533-97-6, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.50533-97-6, Name is N,N-Dimethylpiperidin-4-amine, molecular formula is C7H16N2. In a Article£¬once mentioned of 50533-97-6
Discovery of potent furan piperazine sodium channel blockers for treatment of neuropathic pain
The synthesis and pharmacological characterization of a novel furan-based class of voltage-gated sodium channel blockers is reported. Compounds were evaluated for their ability to block the tetrodotoxin-resistant sodium channel Nav1.8 (PN3) as well as the Nav1.2 and Nav1.5 subtypes. Benchmark compounds from this series possessed enhanced potency, oral bioavailability, and robust efficacy in a rodent model of neuropathic pain, together with improved CNS and cardiovascular safety profiles compared to the clinically used sodium channel blockers mexiletine and lamotrigine.
The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 50533-97-6 is helpful to your research. Synthetic Route of 50533-97-6
Reference£º
Piperidine – Wikipedia,
Piperidine | C5H3729N – PubChem